CA2522787A1 - Systems and methods for correcting high order aberrations in laser refractive surgery - Google Patents

Systems and methods for correcting high order aberrations in laser refractive surgery Download PDF

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CA2522787A1
CA2522787A1 CA002522787A CA2522787A CA2522787A1 CA 2522787 A1 CA2522787 A1 CA 2522787A1 CA 002522787 A CA002522787 A CA 002522787A CA 2522787 A CA2522787 A CA 2522787A CA 2522787 A1 CA2522787 A1 CA 2522787A1
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adjusted
variable
factor
variable comprises
high order
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CA2522787C (en
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Guangming Dai
Junzhong Liang
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AMO Manufacturing USA LLC
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Visx, Incorporated
Guangming Dai
Junzhong Liang
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A61F9/008—Methods or devices for eye surgery using laser
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A61F9/008—Methods or devices for eye surgery using laser
    • A61F9/00802—Methods or devices for eye surgery using laser for photoablation
    • A61F9/00804—Refractive treatments
    • A61F9/00806—Correction of higher orders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A61F9/008—Methods or devices for eye surgery using laser
    • A61F2009/00844—Feedback systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A61F9/008—Methods or devices for eye surgery using laser
    • A61F2009/00844—Feedback systems
    • A61F2009/00846—Eyetracking
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A61F9/008—Methods or devices for eye surgery using laser
    • A61F2009/00844—Feedback systems
    • A61F2009/00848—Feedback systems based on wavefront
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A61F9/008—Methods or devices for eye surgery using laser
    • A61F2009/00855—Calibration of the laser system
    • A61F2009/00857—Calibration of the laser system considering biodynamics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A61F9/008—Methods or devices for eye surgery using laser
    • A61F2009/00861—Methods or devices for eye surgery using laser adapted for treatment at a particular location
    • A61F2009/00872—Cornea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A61F9/008—Methods or devices for eye surgery using laser
    • A61F2009/00878—Planning
    • A61F2009/0088—Planning based on wavefront
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A61F9/008—Methods or devices for eye surgery using laser
    • A61F2009/00897—Scanning mechanisms or algorithms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A61F9/008—Methods or devices for eye surgery using laser
    • A61F9/00802—Methods or devices for eye surgery using laser for photoablation
    • A61F9/00817—Beam shaping with masks

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  • Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Optics & Photonics (AREA)
  • Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Laser Surgery Devices (AREA)
  • Eye Examination Apparatus (AREA)

Abstract

Optical correction methods, devices, and systems reduce optical aberrations or inhibit refractive surgery induced aberrations. Error source control and adjustment or optimization of ablation profiles or other optical data address high order aberrations. A simulation approach identifies and characterizes system factors that can contribute to, or that can be adjusted to inhibit, optical aberrations. Modeling effects of system components facilitates adjustment of the system parameters.

Claims (84)

1. A method of inhibiting an induced aberration resulting from refractive surgery, the method comprising:
(a) inputting a target optical surface shape;
(b) determining a model optical surface shape based on the target optical surface shape and a set of refractive surgery system parameters;
(c) comparing the target optical surface shape and the model optical surface shape to determine an aberration induced by the set of refractive surgery system parameters; and (d) adjusting the set of refractive surgery system parameters so as to inhibit the induced aberration.
2. The method of claim 1, wherein the set of refractive surgery system parameters comprises at least one member selected from the group consisting of a wavefront device variable, a laser ablation profile variable, a laser registration and tracking system variable, a microkeratome variable, and a healing effect variable.
3. The method of claim 1, wherein the adjustment of the set of refractive surgery system parameters is based on a metric selected from the group consisting of an accuracy variable, a heating variable, and a treatment time variable.
4. The method of claim 3, wherein the accuracy variable is based on a root mean squares error factor.
5. The method of claim 3, wherein the heating variable is based on a temperature factor.
6. The method of claim 3, wherein the treatment time variable is based on an ablation time factor.
7. The method of claim 1, wherein the aberration comprises a high order aberration.
8. The method of claim 1, wherein the target optical surface shape is configured to address a low order aberration.
9. The method of claim 2, wherein the wavefront device variable comprises a member selected from the group consisting of a spot identification factor, an accommodation factor, and a reconstruction factor.
10. The method of claim 9, wherein the reconstruction factor comprises a member selected from a group consisting of uncompensated residual error portion, a measurement error portion, and a remaining error portion.
11. The method of claim 2, wherein the laser ablation profile variable comprises a member selected from the group consisting of a pulse size factor, a spot size variability factor, a beam uniformity factor, and a laser pulse repetition rate factor.
12. The method of claim 2, wherein the microkeratome variable comprises a member selected from the group consisting of a central flattening and peripheral thickening effect factor and a hinge effect factor.
13. The method of claim 2, wherein the laser registration and tracking system variable comprises a member selected from the group consisting of a registration factor, a linear tracking factor, and a torsional tracking factor.
14. The method of claim 2, wherein the wavefront device variable is configured to address a high order aberration.
15. The method of claim 2, wherein the wavefront device variable comprises a gridsize factor adjusted to about 100 µm, and the laser ablation profile variable comprises a flying spot scanning factor adjusted to range from about 1 mm to about 1.6 mm.
16. The method of claim 15, wherein the flying spot scanning factor is adjusted to about 1.5 mm.
17. The method of claim 2, wherein the wavefront device variable comprises a spot identification error adjusted to about 0.05 microns.
18. The method of claim 2, wherein the wavefront device variable comprises a wavefront reconstruction error adjusted to about 0.05 microns.
19. The method of claim 2, wherein the wavefront device variable comprises an accommodation error adjusted to about 0.25D, equivalent to about 0.325 microns RMS error for an approximately 6mm pupil.
20. The method of claim 29 wherein the microkeratome variable comprises an induced positive spherical aberration adjusted to between about 0.1 microns and about 0.3 microns.
21. The method of claim 2, wherein the microkeratome variable comprises a coma in the direction of the microkeratome hinge adjusted to between 0.1 microns and 0.3 microns.
22. The method of claim 2, wherein the healing effect variable comprises a Gaussian kernel adjusted to about 2 micron in height and about 0.5mm in full width at half maximum (FWHM).
23. The method of claim 1 wherein the set of refractive surgery system parameters is adjusted such that a post-operative total high order RMS of about 0.3 µm is achieved.
24. The method of claim 23, wherein a pre-operative total high order RMS
is about 0.3 µm.
25. The method of claim 23, wherein each component of the total high order RMS does not exceed about 0.113 µm.
26. The method of claim 1, wherein the set of refractive surgery system parameters is adjusted such that a post-operative total high order RMS of about 0.1 µm is achieved.
27. The method of claim 26, wherein a pre-operative total high order RMS
is about 0.3 µm.
28. The method of claim 26, wherein each component of the total high order RMS does not exceed about 0.038 µm.
29. The method of claim 2, wherein the laser ablation profile variable comprises a variable spot scanning factor, and the laser registration and tracking system variable comprises a registration accuracy adjusted to less than about 10 µm in both the vertical and horizontal directions and a rotational error adjusted to less than about 0.5°.
30. The method of claim 2, wherein the laser ablation profile variable comprises a flying spot scanning factor, and the laser registration and tracking system variable comprises a registration accuracy adjusted to less than about 10 µm in both the vertical and horizontal directions and a rotational error adjusted to less than about 0.5°.
31. The method of claim 2, wherein the laser ablation profile variable comprises a variable spot scanning factor, and the laser registration and tracking system variable comprises a tracking accuracy adjusted to less than about 20 µm in both the vertical and horizontal directions, a latency time adjusted to less than about 10 ms, and a tracking speed adjusted to about 60 Hz or greater.
32. The method of claim 2, wherein the laser ablation profile variable comprises a flying spot scanning factor, and the laser registration and tracking system variable comprises a tracking accuracy adjusted to less than about 5 µm in both the vertical and horizontal directions, a latency time adjusted to less than 5 ms, and a tracking speed adjusted to about 200 Hz or greater.
33. The method of claim 2, wherein the laser ablation profile variable comprises a variable spot scanning factor, and the laser registration and tracking system variable comprises a cyclo-torsional tracking angular accuracy adjusted to 0.5° or better.
34. The method of claim 2, wherein the laser ablation profile variable comprises a flying spot scanning factor, and the laser registration and tracking system variable comprises a cyclo-torsional tracking angular accuracy adjusted to 0.25° or better.
35. The method of claim 2, wherein the laser ablation profile variable comprises a variable spot scanning factor, and the laser registration and tracking system variable comprises a laser energy fluctuation adjusted to less than 4%.
36. The method of claim 2, wherein the laser ablation profile variable comprises a flying spot scanning factor, and the laser registration and tracking system variable comprises a laser energy fluctuation adjusted to less than 2%.
37. The method of claim 2, wherein the target optical surface shape comprises a set of 6-order Zernike polynomials, and the set of refractive surgery system parameters is adjusted such that each component of a post-operative total high order RMS
does not exceed about 0.022 µm.
38. The method of claim 2, wherein the target optical surface shape comprises a set of 6-order Zernike polynomials, and the set of refractive surgery system parameters is adjusted such that each component of a post-operative total high order RMS
does not exceed about 0.0073 µm.
39. The method of claim 1, wherein the set of refractive surgery system parameters is adjusted such that a post-operative total high order RMS is substantially equivalent to a pre-operative total high order RMS.
40. The method of claim 1, wherein the set of refractive surgery system parameters is adjusted such that a post-operative total high order RMS is less than a pre-operative total high order RMS.
41. The method of claim 1, wherein the set of refractive surgery system parameters is adjusted such that a post-operative total high order RMS is about one third the amount of a pre-operative total high order RMS.
42. A method of altering aberration distribution resulting from optical surface refractive surgery, the method comprising:
(a) inputting a target optical surface shape;
(b) determining a model optical surface shape based on the target optical surface shape and a set of refractive surgery system parameters;
(c) comparing the target optical surface shape and the model optical surface shape to determine an aberration distribution; and (d) adjusting the set of refractive surgery system parameters so as to alter the aberration distribution.
43. A method of inhibiting a refractive surgery induced aberration, the method comprising:
(a) inputting a target optical surface shape;
(b) determining a model optical surface shape based on the target optical surface shape and a set of refractive surgery system parameters, the model optical surface shape having an aberration; and (c) adjusting the set of refractive surgery system parameters so as to inhibit the aberration.
44. A system for inhibiting an induced aberration resulting from refractive surgery, the system comprising:
(a) an input that accepts a target optical surface shape;
(b) a module that determines a model optical surface shape based on the target optical surface shape and a set of refractive surgery system parameters; and (c) a module that adjusts the set of refractive surgery system parameters so as to inhibit an aberration in the model optical surface shape.
45. The system of claim 44, wherein the set of refractive surgery system parameters comprises at least one member selected from the group consisting of a wavefront device variable, a laser ablation profile variable, a laser registration and tracking system variable, a microkeratome variable, and a healing effect variable.
46. The system of claim 44, wherein the module that adjusts the refractive surgery system parameters comprises a metric selected from the group consisting of an accuracy variable, a heating variable, and a treatment time variable.
47. The system of claim 46, wherein the accuracy variable is based on a root mean squares error factor.
48. The system of claim 46, wherein the heating variable is based on a temperature factor.
49. The system of claim 46, wherein the treatment time variable is based on an ablation time factor.
50. The system of claim 44, wherein the aberration comprises a high order aberration.
51. The system of claim 44, wherein the target optical surface shape is configured to address a low order aberration.
52. The system of claim 45, wherein the wavefront device variable comprises a member selected from a group consisting of a spot identification factor, an accommodation factor, and a reconstruction factor.
53. The system of claim 52, wherein the reconstruction factor comprises a member selected from the group consisting of uncompensated residual error portion, a measurement error portion, and a remaining error portion.
54. The system of claim 45, wherein the laser ablation profile variable comprises a member selected from the group consisting of a pulse size factor, a spot size variability factor, a beam uniformity factor, and a laser pulse repetition rate factor.
55. The system of claim 45, wherein the microkeratome variable comprises a member selected from the group consisting of a central flattening and peripheral thickening effect factor and a hinge effect factor.
56. The system of claim 45, wherein the laser registration and tracking system variable comprises a member selected from the group consisting of a registration factor, a linear tracking factor, and a torsional tracking factor.
57. The system of claim 45, wherein the wavefront device variable is configured to address a high order aberration.
58. The system of claim 45, wherein the wavefront device variable comprises a gridsize factor adjusted to about 100 µm, and the laser ablation profile variable comprises a flying spot scanning factor adjusted to range from about 1 mm to about 1.6 mm.
59. The system of claim 58, wherein the flying spot scanning factor is about 1.5 mm.
60. The system of claim 45, wherein the wavefront device variable comprises a spot identification error adjusted to about 0.05 microns.
61. The system of claim 45, wherein the wavefront device variable comprises a wavefront reconstruction error adjusted to about 0.05 microns.
62. The system of claim 45, wherein the wavefront device variable comprises an accommodation error adjusted to about 0.25D, equivalent to 0.325 microns RMS error for a 6mm pupil.
63. The system of claim 45, wherein the microkeratorne variable comprises an induced positive spherical aberration adjusted to between about 0.1 microns and about 0.3 microns.
64. The system of claim 45, wherein the microkeratome variable comprises a coma in the direction of the microkeratome hinge adjusted to an amount between 0.1 microns and 0.3 microns.
65. The system of claim 45, wherein the healing effect variable comprises a Gaussian kernel adjusted to about 2 micron in height and about 0.5mm in full width at half maximum (FWHM).
66. The system of claim 44 wherein the set of refractive surgery system parameters is adjusted such that a post-operative total high order RMS of about 0.3 µm is achieved.
67. The system of claim 66, wherein a pre-operative total high order RMS
is about 0.3 µm.
68. The system of claim 66, wherein each component of the total high order RMS does not exceed about 0.13 µm.
69. The system of claim 44, wherein the set of refractive surgery system parameters is adjusted such that a post-operative total high order RMS of about 0.1 µm is achieved.
70. The system of claim 69, wherein a pre-operative total high order RMS
is about 0.3 µm.
71. The system of claim 69, wherein each component of the total high order IBS does not exceed about 0.045 µm.
72. The system of claim 459 wherein the laser ablation profile variable comprises a variable spot scanning factor, and the laser registration and tracking system variable comprises a registration accuracy adjusted to less than 10 µm in both the vertical and horizontal directions and a rotational error adjusted to less than 0.5°.
73. The system of claim 45, wherein the laser ablation profile variable comprises a flying spot scanning factor, and the laser registration and tracking system variable comprises a registration accuracy adjusted to less than 10 µm in both the vertical and horizontal directions and a rotational error adjusted to less than 0.5°.
74. The system of claim 45, wherein the laser ablation profile variable comprises a variable spot scanning factor, and the laser registration and tracking system variable comprises a tracking accuracy adjusted to less than 20 µm in both the vertical and horizontal directions, a latency time adjusted to less than 10 ms, and a tracking speed adjusted to 60 Hz or greater.
75. The system of claim 45, wherein the laser ablation profile variable comprises a flying spot scanning factor, and the laser registration and tracking system variable comprises a tracking accuracy adjusted to less than 5 µm in both the vertical and horizontal directions, a latency time adjusted to less than 5 ms, and a tracking speed adjusted to 200 Hz or greater.
76. The system of claim 45, wherein the laser ablation profile variable comprises a variable spot scanning factor, and the laser registration and tracking system variable comprises a cyclo-torsional tracking angular accuracy adjusted to 0.5° or better.
77. The system of claim 45, wherein the laser ablation profile variable comprises a flying spot scanning factor, and the laser registration and tracking system variable comprises a cyclo-torsional tracking angular accuracy adjusted to 0.25° or better.
78. The system of claim 45, wherein the laser ablation profile variable comprises a variable spot scanning factor, and the laser registration and tracking system variable comprises a laser energy fluctuation adjusted to less than 4%.
79. The system of claim 45, wherein the laser ablation profile variable comprises a flying spot scanning factor, and the laser registration and tracking system variable comprises a laser energy fluctuation adjusted to less than 2%.
80. The system of claim 45, wherein, the target optical surface shape comprises a set of 6-order Zernike polynomials, and the set of refractive surgery system parameters is adjusted such that each component of a post-operative total high order RMS
does not exceed about 0.025 µm.
81. The system of claim 45, wherein the target optical surface shape comprises a set of 6-order Zernike polynomials, and the set of refractive surgery system parameters is adjusted such that each component of a post-operative total high order RMS
does not exceed about 0.0087 µm.
82. The system of claim 44, wherein the set of refractive surgery system parameters is adjusted such that a post-operative total high order RMS is substantially equivalent to a pre-operative total high order RMS.
83. The system of claim 44, wherein the set of refractive surgery system parameters is adjusted such that a post-operative total high order RMS is less than a pre-operative total high order RMS.
84. The system of claim 44, wherein the set of refractive surgery system parameters is adjusted such that a post-operative total high order RMS is about one third the amount of a pre-operative total high order RMS.
CA2522787A 2003-04-18 2004-04-16 Systems and methods for correcting high order aberrations in laser refractive surgery Expired - Fee Related CA2522787C (en)

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US46387303P 2003-04-18 2003-04-18
US60/463,873 2003-04-18
PCT/US2004/012025 WO2004095187A2 (en) 2003-04-18 2004-04-16 Systems and methods for correcting high order aberrations in laser refractive surgery

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EP (1) EP1615575B1 (en)
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EP1617751B1 (en) 2003-04-09 2016-05-04 AMO Manufacturing USA, LLC Wavefront calibration analyzer and methods
US20130190736A1 (en) * 2003-04-18 2013-07-25 Amo Manufacturing Usa, Llc Systems and methods for correcting high order aberrations in laser refractive surgery
MXPA05011131A (en) * 2003-04-18 2006-03-10 Visx Inc Systems and methods for correcting high order aberrations in laser refractive surgery.
US9161815B2 (en) * 2004-06-21 2015-10-20 Kilolambda Technologies Ltd. Dermatological laser system and Method for Skin Resurfacing
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