CA2490857A1 - Particulate therapeutic agent delivery device and method - Google Patents

Particulate therapeutic agent delivery device and method Download PDF

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Publication number
CA2490857A1
CA2490857A1 CA002490857A CA2490857A CA2490857A1 CA 2490857 A1 CA2490857 A1 CA 2490857A1 CA 002490857 A CA002490857 A CA 002490857A CA 2490857 A CA2490857 A CA 2490857A CA 2490857 A1 CA2490857 A1 CA 2490857A1
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CA
Canada
Prior art keywords
gas
delivery device
respiratory
channel
particulate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002490857A
Other languages
French (fr)
Other versions
CA2490857C (en
Inventor
Bradley P. Fuhrman
Mark S. Dowhy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Research Foundation of State University of New York
Original Assignee
The Research Foundation Of State University Of New York
Bradley P. Fuhrman
Mark S. Dowhy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Research Foundation Of State University Of New York, Bradley P. Fuhrman, Mark S. Dowhy filed Critical The Research Foundation Of State University Of New York
Publication of CA2490857A1 publication Critical patent/CA2490857A1/en
Application granted granted Critical
Publication of CA2490857C publication Critical patent/CA2490857C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/22—Carbon dioxide-absorbing devices ; Other means for removing carbon dioxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/01—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes specially adapted for anaesthetising
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/08—Bellows; Connecting tubes ; Water traps; Patient circuits
    • A61M16/0883—Circuit type
    • A61M16/0891—Closed circuit, e.g. for anaesthesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/10—Preparation of respiratory gases or vapours
    • A61M16/104—Preparation of respiratory gases or vapours specially adapted for anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes

Landscapes

  • Health & Medical Sciences (AREA)
  • Anesthesiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Devices For Medical Bathing And Washing (AREA)

Abstract

A particulate therapeutic agent delivery device (10) and method are disclose d. In an embodiment of the device there is a respiratory-gas channel (13) havin g a patient end (16) to which a patient may be pneumatically connected, a particulate-~therapeutic-agent channel (19) in pneumatic communication with the respiratory-gas channel, a scrubber housing (22) in pneumatic communication with the respiratory-gas channel, the scrubber housing having an expired-gas orifice (25) for receiving expired gas from the respiratory-gas- channel, and a scrubber material (26) situated within the housing so as to receive expired gas via the expired-gas orifice and remove carbon dioxide fr om the expired gas to provide treated gas, and situated so as to provide the treated gas to the respiratory-gas channel.

Claims (19)

1. A particulate therapeutic agent delivery device comprising:
a respiratory-gas channel having a patient end to which a patient may be pneumatically connected;
a particulate-therapeutic-agent channel in pneumatic communication with the respiratory-gas channel;
a scrubber housing in pneumatic communication with the respiratory-gas channel, the scrubber housing having an expired-gas orifice for receiving expired gas from the respiratory-gas-channel; and a scrubber material situated within the housing so as to receive expired gas via the expired-gas orifice and remove carbon dioxide from the expired gas to provide treated gas, and situated so as to provide the treated gas to the respiratory-gas channel.
2. The delivery device of claim 1, wherein the particulate-therapeutic-agent channel is in pneumatic communication with an agent delivery location on the respiratory-gas channel, the agent delivery location being located so that a general flow of gas from the expired-gas orifice to the patient end passes by the agent delivery location.
3. The delivery device of claim 1, further comprising an aerosol generator in pneumatic communication with the particulate-therapeutic-agent channel.
4. The delivery device of claim 1, wherein the aerosol generator is a nebulizer.
5. The delivery device of claim 1, further comprising a first channel from the respiratory-gas channel to the aerosol generator, and a second channel from the aerosol generator to the respiratory-gas channel.
6. The delivery device of claim 1, wherein the scrubber housing includes an electrically conductive material.
7. The delivery device of claim 1, wherein the scrubber material is soda-lime.
8. The delivery device of claim 1, wherein the scrubber housing has a treated-gas orifice, and the delivery device further comprises a treated-gas channel situated so as to provide pneumatic communication between the treated-gas orifice and the respiratory-gas channel, so that gas that has past through the scrubber housing is delivered to the respiratory-gas channel.
9. The delivery device of claim 1, further comprising a check valve positioned and oriented in the delivery device to encourage particulate therapeutic agent in the respiratory-gas channel to flow generally toward the patient end during inspiration.
10. The delivery device of claim 1, further comprising a check valve positioned and oriented in the delivery device to prevent expired gas from bypassing the scrubber housing during expiration.
11. The delivery device of claim 1, further comprising a ventilator in pneumatic communication with the respiratory-gas channel.
12. The delivery device of claim 1, wherein the particulate-therapeutic-agent channel has therein a particulate therapeutic agent.
13. The delivery device of claim 12, wherein the particulate therapeutic agent is a liquid.
14. The delivery device of claim 12, wherein the particulate therapeutic agent is a solid.
15. A method of delivering a particulate therapeutic agent, comprising:
providing a patient having a respiratory system;
providing a particulate therapeutic agent to the respiratory system;
providing a carbon dioxide scrubber in pneumatic communication with the respiratory system;
providing expired gas from the respiratory system to the scrubber;
passing the expired gas through the scrubber to provide treated gas; and providing the treated gas to the respiratory system.
16. The method of claim 15, further comprising:
providing a ventilator; and moving the ventilator to force the therapeutic agent into the respiratory system.
17. The method of claim 15 wherein providing the therapeutic agent includes nebulizing the therapeutic agent.
18. The delivery device of claim 15, wherein the particulate therapeutic agent is a liquid.
19. The delivery device of claim 15, wherein the particulate therapeutic agent is a solid.
CA2490857A 2002-06-28 2003-06-30 Particulate therapeutic agent delivery device and method Expired - Fee Related CA2490857C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US39231402P 2002-06-28 2002-06-28
US60/392,314 2002-06-28
PCT/US2003/020532 WO2004002390A2 (en) 2002-06-28 2003-06-30 Therapeutic agent delivery device and method

Publications (2)

Publication Number Publication Date
CA2490857A1 true CA2490857A1 (en) 2004-01-08
CA2490857C CA2490857C (en) 2011-08-30

Family

ID=30000843

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2490857A Expired - Fee Related CA2490857C (en) 2002-06-28 2003-06-30 Particulate therapeutic agent delivery device and method

Country Status (9)

Country Link
US (1) US7367335B2 (en)
EP (2) EP1558312B1 (en)
JP (1) JP2005531373A (en)
AU (1) AU2003247834A1 (en)
CA (1) CA2490857C (en)
ES (1) ES2651342T3 (en)
HK (1) HK1254943A1 (en)
MX (1) MXPA05000223A (en)
WO (1) WO2004002390A2 (en)

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FR2906710B1 (en) * 2006-10-05 2008-12-12 Equip Veterinaire Minerve Sa SAFETY ANESTHESIA DEVICE FOR MEDICAL SAMPLES CARRIED OUT WITH HIGH CADENCE ON SMALL LABORATORY ANIMALS
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US8151794B2 (en) 2007-04-24 2012-04-10 Trudell Medical International Aerosol delivery system
EP2150302A1 (en) * 2007-05-08 2010-02-10 The Research Foundation Of State University Of New York Breathing-gas delivery system with exhaust gas filter body and method of operating a breathing-gas delivery system
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US8118713B2 (en) 2008-02-21 2012-02-21 Trudell Medical International Respiratory muscle endurance training device and method for the use thereof
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WO2013166430A2 (en) 2012-05-04 2013-11-07 Trustees Of The University Of Pennsylvania System for delivery of gaseous imaging contrast agents and methods for using same
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Also Published As

Publication number Publication date
JP2005531373A (en) 2005-10-20
WO2004002390A2 (en) 2004-01-08
US20040003808A1 (en) 2004-01-08
WO2004002390A3 (en) 2004-04-29
AU2003247834A1 (en) 2004-01-19
AU2003247834A8 (en) 2004-01-19
ES2651342T3 (en) 2018-01-25
HK1254943A1 (en) 2019-08-02
EP1558312B1 (en) 2017-08-09
CA2490857C (en) 2011-08-30
US7367335B2 (en) 2008-05-06
MXPA05000223A (en) 2005-07-15
EP3335752A1 (en) 2018-06-20
EP1558312A4 (en) 2010-01-20
EP1558312A2 (en) 2005-08-03

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Effective date: 20200831