CA2335914A1 - Utilisation de solutions salines isoosmotiques, leur procede de preparation et medicament a base de ces solutions - Google Patents

Utilisation de solutions salines isoosmotiques, leur procede de preparation et medicament a base de ces solutions Download PDF

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Publication number
CA2335914A1
CA2335914A1 CA002335914A CA2335914A CA2335914A1 CA 2335914 A1 CA2335914 A1 CA 2335914A1 CA 002335914 A CA002335914 A CA 002335914A CA 2335914 A CA2335914 A CA 2335914A CA 2335914 A1 CA2335914 A1 CA 2335914A1
Authority
CA
Canada
Prior art keywords
solutions
iso
preparing same
medicine based
saline solutions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002335914A
Other languages
English (en)
Other versions
CA2335914C (fr
Inventor
Jean-Claude Yvin
Olivier Tabary
Jacky Jacquot
Edith Puchelle
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoire de la Mer SAS
Original Assignee
Laboratoires Goemar S.A.
Jean-Claude Yvin
Olivier Tabary
Jacky Jacquot
Edith Puchelle
Laboratoire De La Mer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoires Goemar S.A., Jean-Claude Yvin, Olivier Tabary, Jacky Jacquot, Edith Puchelle, Laboratoire De La Mer filed Critical Laboratoires Goemar S.A.
Publication of CA2335914A1 publication Critical patent/CA2335914A1/fr
Application granted granted Critical
Publication of CA2335914C publication Critical patent/CA2335914C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/02—Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
    • A61K35/08—Mineral waters; Sea water
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/04—Drugs for disorders of the respiratory system for throat disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Abstract

L'invention a pour objet l'utilisation de solutions salines isoosmotiques, notamment obtenues à partir de l'eau de mer, pour l'obtention d'un médicament destiné à un traitement pour la prévention et la limitation de la libération des médiateurs chimiques responsables du déclenchement des phénomènes inflammatoires des muqueuses des voies respiratoires humaines.

Claims (2)

1. Utilisation d'eau de mer rendue isoosmatique, pour l'obtention d'un médicament destiné à un traitement pour la prévention et la limitation de la libération, --sous l'influence des agents pro-inflammatoires comprenant des substances d'origine bactérienne, les virus, les bactéries et tous autres éléments irritants et allergisants transportés par l'air respiré--, des médiateurs chimiques responsables du déclenchement des phénomènes inflammatoires des muqueuses des voies respiratoires humaines.
2. Utilisation selon la revendication 1 d'eau de mer rendue isoosmotique caractérisée :
- par un pH de 7,8 à 8,3 - par une densité de 1,008 à 1,01 - par une teneur en matières sèches de 1 à 2% en poids - par une osmolarité de 305 à 315 mOs/kg et - par une constitution chimique résultant, pour ce qui est de ses principaux éléments, du tableau A ci-après :
TABLEAU A
sodium (Na) de 2000 à 2600 mg/l Potassium (K) de 40 à 80 mg/l Chlorures (Cl) de 5800 à 6000 mg/l Calcium (Ca) de 300 à 400 mg/l Magnesium (Mg) de 1200 à 1500 mg/l
CA002335914A 1998-06-29 1999-06-29 Utilisation de solutions salines isoosmotiques, leur procede de preparation et medicament a base de ces solutions Expired - Fee Related CA2335914C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9808250A FR2780285B1 (fr) 1998-06-29 1998-06-29 Utilisation de solutions salines isoosmotiques, leur procede de preparation et medicaments anti-inflammatoires a base de ces solutions
FR98/08250 1998-06-29
PCT/FR1999/001565 WO2000000209A2 (fr) 1998-06-29 1999-06-29 Utilisation de solutions salines isoosmotiques, leur procede de preparation et medicament a base de ces solutions

Publications (2)

Publication Number Publication Date
CA2335914A1 true CA2335914A1 (fr) 2000-01-06
CA2335914C CA2335914C (fr) 2009-11-10

Family

ID=9528004

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002335914A Expired - Fee Related CA2335914C (fr) 1998-06-29 1999-06-29 Utilisation de solutions salines isoosmotiques, leur procede de preparation et medicament a base de ces solutions

Country Status (12)

Country Link
US (1) US6451352B1 (fr)
EP (1) EP1091747B1 (fr)
JP (1) JP2002519331A (fr)
AT (1) ATE259237T1 (fr)
AU (1) AU4376699A (fr)
CA (1) CA2335914C (fr)
DE (1) DE69914756T2 (fr)
DK (1) DK1091747T3 (fr)
ES (1) ES2216519T3 (fr)
FR (1) FR2780285B1 (fr)
PT (1) PT1091747E (fr)
WO (1) WO2000000209A2 (fr)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2780650B1 (fr) * 1998-07-03 2000-09-08 Goemar Lab Sa Solutions salines, leur procede de preparation et medicaments a base de ces solutions
US6861001B2 (en) * 1999-12-02 2005-03-01 The General Hospital Corporation Methods for removal, purification, and concentration of viruses, and methods of therapy based thereupon
FR2803205B1 (fr) * 1999-12-31 2002-10-18 Goemar Lab Sa Solutions ioniques aqueuses et leurs utilisations notamment en ophtalmologie
ES2237477T3 (es) * 2000-11-22 2005-08-01 D.M.G. Italia Srl Preparacion para reforzar la respuesta inmunitaria en el anillo de waldeyer y la mucosa buconasal mediante una administracion intranasal.
JP2002212081A (ja) * 2001-01-23 2002-07-31 Goshu Yakuhin Kk 海洋深層水配合鼻洗浄剤
US7097852B1 (en) * 2003-05-09 2006-08-29 Soto Jose A Solution comprising sea water as expectorant and virucidal for the treatment of respiratory diseases and method to use and develop
US20050100637A1 (en) * 2003-11-12 2005-05-12 Robert Murray Carbohydrate and electrolyte replacement composition
US20050207983A1 (en) * 2004-03-05 2005-09-22 Pulmatrix, Inc. Formulations decreasing particle exhalation
FR2872046B1 (fr) * 2004-06-28 2006-09-15 Pascal Hemmery Compostion a base d'eau de mer, son procede de preparation, son utilisation pour l'hygiene de l'appareil genital feminin et dispositif pour son utilisation
CA2608752A1 (fr) * 2005-05-18 2006-11-23 Pulmatrix Inc. Formulations pour la modification de proprietes biophysiques des muqueuses
FR2915389B1 (fr) * 2007-04-26 2012-12-21 De La Mer Laboratoire Utilisation de solutions ioniques isoosmotiques a base d'eau de mer pour la fabrication de dispositifs medicaux pour la prevention des complications du rhume courant
US8435590B2 (en) 2008-11-24 2013-05-07 Stokely-Van Camp, Inc. Use of novel carbohydrates and carbohydrate blends to provide a sports beverage with increased absorption
CN105640925B (zh) 2010-08-30 2019-08-16 普马特里克斯营业公司 干燥粉末配方及用于治疗肺部疾病的方法
EP2464346A1 (fr) 2010-08-30 2012-06-20 Pulmatrix, Inc. Méthodes de traitement de la mucoviscidose
CA2812417C (fr) 2010-09-29 2019-10-22 Pulmatrix, Inc. Poudres seches cationiques
KR101915241B1 (ko) 2010-09-29 2018-11-06 풀매트릭스 오퍼레이팅 컴퍼니, 인크 흡입용의 1가 금속 양이온 건조 분말
FR2971713B1 (fr) 2011-02-18 2019-03-29 Laboratoire De La Mer Solution ionique aqueuse contenant de l'eau de mer et au moins un compose originellement non miscible a l'eau de mer.
CN109999013A (zh) 2012-02-29 2019-07-12 普马特里克斯营业公司 可吸入干粉剂
WO2013134293A1 (fr) 2012-03-05 2013-09-12 Duke University Vaccin
FR2994389B1 (fr) * 2012-08-10 2014-10-10 De La Mer Laboratoire Composition pour le lavage ou le traitement des cavites naso-sinusiennes
RU2015146871A (ru) 2013-04-01 2017-05-10 Пулматрикс, Инк. Сухие порошки с тиотропием
PT3076983T (pt) * 2013-12-03 2019-10-31 Gerolymatos Int S A Composições aquosas iónicas
EP3236933B1 (fr) 2014-12-24 2018-11-14 JADRAN - GALENSKI LABORATORIJ d.d. Composition nasale contenant de l'eau de mer en tant qu'excipient d'amélioration de stabilité
FR3034315B1 (fr) * 2015-04-02 2017-05-26 De La Mer Laboratoire Solution ionique aqueuse, a base de sels mineraux dissous, notamment destinee aux soins de la gorge
KR102227420B1 (ko) 2017-06-30 2021-03-15 대봉엘에스 주식회사 비강 세정용 조성물

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1313142C (fr) 1987-07-29 1993-01-26 Nabil Hazzi Solution d'eau de mer hypertonique therapeutique
FR2688133A1 (fr) * 1992-03-06 1993-09-10 Plantes Tropicales Lab Composition d'hygiene a base d'eau de mer.
FR2769503B1 (fr) * 1997-10-10 1999-12-17 Renee Jane Maugendre Composition a base d'eau de mer destinee au lavage des fosses nasales
FR2778562B1 (fr) * 1998-05-14 2000-08-04 Sephra Composition pharmaceutique, hygienique et/ou cosmetique contenant de l'eau de mer et de l'arginine

Also Published As

Publication number Publication date
DK1091747T3 (da) 2004-06-14
ES2216519T3 (es) 2004-10-16
EP1091747A2 (fr) 2001-04-18
EP1091747B1 (fr) 2004-02-11
PT1091747E (pt) 2004-06-30
CA2335914C (fr) 2009-11-10
WO2000000209A3 (fr) 2000-03-16
FR2780285A1 (fr) 1999-12-31
WO2000000209A2 (fr) 2000-01-06
DE69914756T2 (de) 2004-09-23
US6451352B1 (en) 2002-09-17
JP2002519331A (ja) 2002-07-02
DE69914756D1 (de) 2004-03-18
ATE259237T1 (de) 2004-02-15
AU4376699A (en) 2000-01-17
FR2780285B1 (fr) 2001-10-05

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Effective date: 20160629