CA2297340A1 - Monster capillary array electrophoresis scanner - Google Patents

Monster capillary array electrophoresis scanner Download PDF

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Publication number
CA2297340A1
CA2297340A1 CA002297340A CA2297340A CA2297340A1 CA 2297340 A1 CA2297340 A1 CA 2297340A1 CA 002297340 A CA002297340 A CA 002297340A CA 2297340 A CA2297340 A CA 2297340A CA 2297340 A1 CA2297340 A1 CA 2297340A1
Authority
CA
Canada
Prior art keywords
monster
capillary array
array electrophoresis
scanner
electrophoresis scanner
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002297340A
Other languages
French (fr)
Other versions
CA2297340C (en
Inventor
Richard A. Mathies
James R. Scherer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Affymetrix Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2297340A1 publication Critical patent/CA2297340A1/en
Application granted granted Critical
Publication of CA2297340C publication Critical patent/CA2297340C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44704—Details; Accessories
    • G01N27/44717—Arrangements for investigating the separated zones, e.g. localising zones
    • G01N27/44721—Arrangements for investigating the separated zones, e.g. localising zones by optical means
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44756—Apparatus specially adapted therefor
    • G01N27/44782—Apparatus specially adapted therefor of a plurality of samples

Abstract

A Monster Capillary Array Electrophoresis scanner measures four-color electropherograms from over a thousand capillary electrophoretic separations in parallel.
The system consists of a two-dimensional confocal rotary scanner and a four-color detection unit.
CA002297340A 1999-01-27 2000-01-27 Monster capillary array electrophoresis scanner Expired - Fee Related CA2297340C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/238,131 1999-01-27
US09/238,131 US6270644B1 (en) 1999-01-27 1999-01-27 Capillary array electrophoresis scanner

Publications (2)

Publication Number Publication Date
CA2297340A1 true CA2297340A1 (en) 2000-07-27
CA2297340C CA2297340C (en) 2004-03-30

Family

ID=22896639

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002297340A Expired - Fee Related CA2297340C (en) 1999-01-27 2000-01-27 Monster capillary array electrophoresis scanner

Country Status (4)

Country Link
US (3) US6270644B1 (en)
EP (1) EP1024360A3 (en)
JP (1) JP2000227415A (en)
CA (1) CA2297340C (en)

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US7875440B2 (en) 1998-05-01 2011-01-25 Arizona Board Of Regents Method of determining the nucleotide sequence of oligonucleotides and DNA molecules
US6780591B2 (en) 1998-05-01 2004-08-24 Arizona Board Of Regents Method of determining the nucleotide sequence of oligonucleotides and DNA molecules
US6270644B1 (en) * 1999-01-27 2001-08-07 Affymetrix, Inc. Capillary array electrophoresis scanner
JP4175735B2 (en) * 1999-05-12 2008-11-05 独立行政法人理化学研究所 Multi-capillary electrophoresis device
US6818395B1 (en) * 1999-06-28 2004-11-16 California Institute Of Technology Methods and apparatus for analyzing polynucleotide sequences
US6533914B1 (en) * 1999-07-08 2003-03-18 Shaorong Liu Microfabricated injector and capillary array assembly for high-resolution and high throughput separation
US6406604B1 (en) * 1999-11-08 2002-06-18 Norberto A. Guzman Multi-dimensional electrophoresis apparatus
US7329388B2 (en) 1999-11-08 2008-02-12 Princeton Biochemicals, Inc. Electrophoresis apparatus having staggered passage configuration
JP2001255301A (en) * 2000-03-08 2001-09-21 Shimadzu Corp Electrophoretic apparatus
US6805784B2 (en) * 2000-05-15 2004-10-19 Hitachi, Ltd. Capillary array
US6531041B1 (en) * 2000-07-20 2003-03-11 Symyx Technologies, Inc. Multiplexed capillary electrophoresis system with rotatable photodetector
CA2440754A1 (en) * 2001-03-12 2002-09-19 Stephen Quake Methods and apparatus for analyzing polynucleotide sequences by asynchronous base extension
ITMI20010566U1 (en) * 2001-10-25 2003-04-25 Troletti Adriano HAIR DRYER, WITH HIGH PRACTICALITY OF USE
EP1329631A3 (en) * 2002-01-22 2003-10-22 Jenbacher Zündsysteme GmbH Combustion engine
US8007724B2 (en) * 2003-11-07 2011-08-30 Princeton Biochemicals, Inc. Electrophoresis apparatus having at least one auxiliary buffer passage
WO2005047882A2 (en) * 2003-11-07 2005-05-26 Princeton Biochemicals, Inc. Multi-dimensional electrophoresis apparatus
US7169560B2 (en) 2003-11-12 2007-01-30 Helicos Biosciences Corporation Short cycle methods for sequencing polynucleotides
US7981604B2 (en) 2004-02-19 2011-07-19 California Institute Of Technology Methods and kits for analyzing polynucleotide sequences
US7211184B2 (en) * 2004-08-04 2007-05-01 Ast Management Inc. Capillary electrophoresis devices
US8057655B1 (en) * 2004-08-20 2011-11-15 The Board Of Trustees Of The Leland Stanford Junior University Sub-micron object control arrangement and approach therefor
US7666593B2 (en) 2005-08-26 2010-02-23 Helicos Biosciences Corporation Single molecule sequencing of captured nucleic acids
US20070131870A1 (en) * 2005-12-12 2007-06-14 Combisep Multiplexed CE fluorescence system
CN101165472B (en) * 2006-10-20 2010-05-12 中国科学院大连化学物理研究所 Multiple-pass mode capillary tube electrophoresis device
WO2009086092A1 (en) * 2007-12-20 2009-07-09 University Of Southern California Usc Stevens An on-column frit-fabrication method for fused silica capilaries
FI120089B (en) * 2008-01-23 2009-06-30 Kone Corp A method of installing a lift
US20090203022A1 (en) * 2008-02-07 2009-08-13 Arizona Board Of Regents For And On Behalf Of Arizona State University Analysis
JP4951578B2 (en) * 2008-04-14 2012-06-13 株式会社日立ハイテクノロジーズ Electrophoresis device
WO2010053342A1 (en) * 2008-11-05 2010-05-14 Morales Villagran Alberto System and method for collecting and reading of fluorescence in capillary tubes
EP2393596B1 (en) * 2009-02-09 2016-09-28 Whitespace Enterprise Corporation Microfluidic devices and methods of providing a storable sample
US8357281B2 (en) * 2009-09-21 2013-01-22 Advanced Analytical Technologies, Inc. Multi-wavelength fluorescence detection system for multiplexed capillary electrophoresis
US9207205B2 (en) * 2009-12-17 2015-12-08 The Curators Of The University Of Missouri Method and apparatus for cancer screening
WO2011106098A2 (en) * 2010-02-25 2011-09-01 Advanced Microlabs, Llc Microfluidic interface for a microchip
CN106018403B (en) * 2016-05-12 2019-05-21 南京擎科生物科技有限公司 The light absorption detector and detection method of capillary array electrophoresis instrument

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IE940110L (en) 1989-03-23 1990-09-23 Bunce Roger A Liquid transfer devices
US5091652A (en) 1990-01-12 1992-02-25 The Regents Of The University Of California Laser excited confocal microscope fluorescence scanner and method
US5274240A (en) 1990-01-12 1993-12-28 The Regents Of The University Of California Capillary array confocal fluorescence scanner and method
ATE154981T1 (en) 1990-04-06 1997-07-15 Perkin Elmer Corp AUTOMATED MOLECULAR BIOLOGY LABORATORY
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IL108497A0 (en) * 1993-02-01 1994-05-30 Seq Ltd Methods and apparatus for dna sequencing
US5372695A (en) 1993-05-07 1994-12-13 Applied Biosystems, Inc. Application specific capillary electrophoresis
US5483075A (en) 1994-11-01 1996-01-09 Perkin-Elmer Corporation Rotary scanning apparatus
US5560811A (en) 1995-03-21 1996-10-01 Seurat Analytical Systems Incorporated Capillary electrophoresis apparatus and method
US5609826A (en) 1995-04-17 1997-03-11 Ontogen Corporation Methods and apparatus for the generation of chemical libraries
JPH09243597A (en) * 1996-03-08 1997-09-19 Shimadzu Corp Multi-capillary dna sequencer
EP0854362A3 (en) * 1997-01-16 2000-12-20 Japan Science and Technology Corporation Multi-capillary electrophoresis apparatus
JP3042487B2 (en) * 1998-01-29 2000-05-15 株式会社日立製作所 Electrophoresis device
US6103083A (en) * 1998-02-20 2000-08-15 Tetragen Capillary electrophoresis apparatus and method
US6270644B1 (en) * 1999-01-27 2001-08-07 Affymetrix, Inc. Capillary array electrophoresis scanner

Also Published As

Publication number Publication date
US6270644B1 (en) 2001-08-07
JP2000227415A (en) 2000-08-15
CA2297340C (en) 2004-03-30
EP1024360A3 (en) 2003-04-09
EP1024360A2 (en) 2000-08-02
US6554986B1 (en) 2003-04-29
US20030150727A1 (en) 2003-08-14
US7090758B2 (en) 2006-08-15

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