CA2274166A1 - Method for monitoring the level of an osmotically active component in body fluid and device for carrying out said method - Google Patents

Method for monitoring the level of an osmotically active component in body fluid and device for carrying out said method Download PDF

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Publication number
CA2274166A1
CA2274166A1 CA002274166A CA2274166A CA2274166A1 CA 2274166 A1 CA2274166 A1 CA 2274166A1 CA 002274166 A CA002274166 A CA 002274166A CA 2274166 A CA2274166 A CA 2274166A CA 2274166 A1 CA2274166 A1 CA 2274166A1
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CA
Canada
Prior art keywords
level
monitoring
carrying
active component
osmotically active
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002274166A
Other languages
French (fr)
Other versions
CA2274166C (en
Inventor
Olav Ellingsen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lifecare AS
Original Assignee
Lifecare A/S
Olav Ellingsen
Osmolife As
Lifecare As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lifecare A/S, Olav Ellingsen, Osmolife As, Lifecare As filed Critical Lifecare A/S
Publication of CA2274166A1 publication Critical patent/CA2274166A1/en
Application granted granted Critical
Publication of CA2274166C publication Critical patent/CA2274166C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N13/00—Investigating surface or boundary effects, e.g. wetting power; Investigating diffusion effects; Analysing materials by determining surface, boundary, or diffusion effects
    • G01N13/04—Investigating osmotic effects
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/66—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood sugars, e.g. galactose

Abstract

A method for monitoring changes in the level of an osmotically active component, such as for instance glucose, or in healthy humans, such as athletes for monitoring the level of lactic acid in the muscles is described.
The key feature of the method is that the osmotic movement back and forth over a membrane is used to activate a sensing device, whereby the physical changes that take place in the fluid may be recorded by a receiver situated outside the body. A device for carrying out said method is likewise described.
CA002274166A 1996-12-23 1997-12-22 Method for monitoring the level of an osmotically active component in body fluid and device for carrying out said method Expired - Lifetime CA2274166C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
NO19965566A NO311817B1 (en) 1996-12-23 1996-12-23 Method for recording the changes in the level of an osmotically active component in body fluid and device for carrying out the method
NO19965566 1996-12-23
PCT/NO1997/000349 WO1998028605A1 (en) 1996-12-23 1997-12-22 Method for monitoring the level of an osmotically active component in body fluid and device for carrying out said method

Publications (2)

Publication Number Publication Date
CA2274166A1 true CA2274166A1 (en) 1998-07-02
CA2274166C CA2274166C (en) 2002-04-09

Family

ID=19900217

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002274166A Expired - Lifetime CA2274166C (en) 1996-12-23 1997-12-22 Method for monitoring the level of an osmotically active component in body fluid and device for carrying out said method

Country Status (7)

Country Link
US (1) US6224550B1 (en)
EP (1) EP0946863A1 (en)
JP (1) JP3913276B2 (en)
AU (1) AU7875098A (en)
CA (1) CA2274166C (en)
NO (1) NO311817B1 (en)
WO (1) WO1998028605A1 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6201980B1 (en) * 1998-10-05 2001-03-13 The Regents Of The University Of California Implantable medical sensor system
US7553280B2 (en) * 2000-06-29 2009-06-30 Sensors For Medicine And Science, Inc. Implanted sensor processing system and method
CA2458966C (en) * 2001-10-23 2013-02-26 Medtronic Minimed, Inc. Method and system for non-vascular sensor implantation
US7810380B2 (en) 2003-03-25 2010-10-12 Tearlab Research, Inc. Systems and methods for collecting tear film and measuring tear film osmolarity
US7905134B2 (en) 2002-08-06 2011-03-15 The Regents Of The University Of California Biomarker normalization
US8020433B2 (en) * 2003-03-25 2011-09-20 Tearlab Research, Inc. Systems and methods for a sample fluid collection device
WO2004017050A1 (en) * 2002-08-06 2004-02-26 The Regents Of The University Of California Tear film osmometry
US7736309B2 (en) 2002-09-27 2010-06-15 Medtronic Minimed, Inc. Implantable sensor method and system
US20080214912A1 (en) * 2007-01-10 2008-09-04 Glucose Sensing Technologies, Llc Blood Glucose Monitoring System And Method
US7734349B2 (en) * 2007-07-18 2010-06-08 Cardiac Pacemakers, Inc. Osmometric heart monitoring device and methods
EP2185910B1 (en) 2007-08-20 2018-07-11 Lifecare AS Apparatus and method for measuring augmented osmotic pressure in a reference cavity
GB2446247B (en) * 2007-11-27 2008-12-17 Robert Joseph Wagener Homeostatic insulin pump
EP2668177B1 (en) * 2011-01-28 2014-10-22 Boehringer Ingelheim International GmbH Substituted pyridinyl-pyrimidines and their use as medicaments
EP3198257B1 (en) 2014-09-23 2020-08-12 Tearlab Research, Inc. System for integration of microfluidic tear collection and lateral flow analysis of analytes of interest
CN107422016A (en) * 2017-07-21 2017-12-01 上海第二工业大学 The preparation method of the minimally invasive glucose sensor of spiral shape implantable of PVA/PEG composite aquogel outer membrane structures

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3187562A (en) 1962-04-10 1965-06-08 Shell Oil Co Apparatus for determining osmotic pressures
US4660568A (en) 1976-06-21 1987-04-28 Cosman Eric R Telemetric differential pressure sensing system and method therefore
US4680268A (en) * 1985-09-18 1987-07-14 Children's Hospital Medical Center Implantable gas-containing biosensor and method for measuring an analyte such as glucose
US4832034A (en) * 1987-04-09 1989-05-23 Pizziconi Vincent B Method and apparatus for withdrawing, collecting and biosensing chemical constituents from complex fluids
US4860577A (en) 1989-01-06 1989-08-29 Southeastern Illinois College Foundation Osmotic applications of hollow fibers
CH677149A5 (en) * 1989-07-07 1991-04-15 Disetronic Ag
US5388449A (en) 1993-07-06 1995-02-14 Leveen; Harry H. Osmolarity sensor
US5711861A (en) * 1995-11-22 1998-01-27 Ward; W. Kenneth Device for monitoring changes in analyte concentration

Also Published As

Publication number Publication date
WO1998028605A1 (en) 1998-07-02
CA2274166C (en) 2002-04-09
NO965566L (en) 1998-06-24
JP3913276B2 (en) 2007-05-09
US6224550B1 (en) 2001-05-01
NO965566D0 (en) 1996-12-23
NO311817B1 (en) 2002-01-28
JP2001506900A (en) 2001-05-29
EP0946863A1 (en) 1999-10-06
AU7875098A (en) 1998-07-17

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Effective date: 20171222