CA2263924A1 - Improved methods for diagnostic imaging involving the use of a contrast agent and a coronary vasodilator - Google Patents

Improved methods for diagnostic imaging involving the use of a contrast agent and a coronary vasodilator

Info

Publication number
CA2263924A1
CA2263924A1 CA002263924A CA2263924A CA2263924A1 CA 2263924 A1 CA2263924 A1 CA 2263924A1 CA 002263924 A CA002263924 A CA 002263924A CA 2263924 A CA2263924 A CA 2263924A CA 2263924 A1 CA2263924 A1 CA 2263924A1
Authority
CA
Canada
Prior art keywords
patient
contrast agent
region
diagnostic imaging
coronary vasodilator
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002263924A
Other languages
French (fr)
Other versions
CA2263924C (en
Inventor
Evan C. Unger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lantheus Medical Imaging Inc
Original Assignee
Imarx Pharmaceutical Corp.
Evan C. Unger
Dupont Contrast Imaging Inc.
Bristol-Myers Squibb Medical Imaging, Inc.
Lantheus Medical Imaging, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24861044&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2263924(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Imarx Pharmaceutical Corp., Evan C. Unger, Dupont Contrast Imaging Inc., Bristol-Myers Squibb Medical Imaging, Inc., Lantheus Medical Imaging, Inc. filed Critical Imarx Pharmaceutical Corp.
Publication of CA2263924A1 publication Critical patent/CA2263924A1/en
Application granted granted Critical
Publication of CA2263924C publication Critical patent/CA2263924C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/41—Detecting, measuring or recording for evaluating the immune or lymphatic systems
    • A61B5/411—Detecting or monitoring allergy or intolerance reactions to an allergenic agent or substance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/227—Liposomes, lipoprotein vesicles, e.g. LDL or HDL lipoproteins, micelles, e.g. phospholipidic or polymeric
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/20—Measuring for diagnostic purposes; Identification of persons for measuring urological functions restricted to the evaluation of the urinary system
    • A61B5/201—Assessing renal or kidney functions

Abstract

Improved method for providing an image of an internal region of a patient, especially the cardiovascular region. Embodiments of the invention involve the administration to the patient of a contrast agent which comprises a vesicle composition comprising lipid or polymer vesicles and a gas or gaseous precursor, in combinationwith a coronary vasodilator. The patient is scanned using diagnostic imaging, such as ultrasound, to obtain a visible image of the region. The methods are particularly useful for diagnosing the presence of diseased tissue in the cardiovascular region of a patient, as well as for measuring blood flow in the cardiovascular region of a patient.
CA002263924A 1996-09-11 1997-08-26 Improved methods for diagnostic imaging involving the use of a contrast agent and a coronary vasodilator Expired - Fee Related CA2263924C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US71217396A 1996-09-11 1996-09-11
US08/712,173 1996-09-11
PCT/US1997/014986 WO1998010799A1 (en) 1996-09-11 1997-08-26 Improved methods for diagnostic imaging involving the use of a contrast agent and a coronary vasodilator

Publications (2)

Publication Number Publication Date
CA2263924A1 true CA2263924A1 (en) 1998-03-19
CA2263924C CA2263924C (en) 2008-11-18

Family

ID=24861044

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002263924A Expired - Fee Related CA2263924C (en) 1996-09-11 1997-08-26 Improved methods for diagnostic imaging involving the use of a contrast agent and a coronary vasodilator

Country Status (7)

Country Link
US (2) US5846517A (en)
EP (2) EP1323434B1 (en)
AU (1) AU732813B2 (en)
CA (1) CA2263924C (en)
DE (1) DE69738223T3 (en)
PT (1) PT1323434E (en)
WO (1) WO1998010799A1 (en)

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