CA2188046A1 - Osmotic system for delivering of fluid-sensitive somatotropin to bovine animals - Google Patents

Osmotic system for delivering of fluid-sensitive somatotropin to bovine animals

Info

Publication number
CA2188046A1
CA2188046A1 CA002188046A CA2188046A CA2188046A1 CA 2188046 A1 CA2188046 A1 CA 2188046A1 CA 002188046 A CA002188046 A CA 002188046A CA 2188046 A CA2188046 A CA 2188046A CA 2188046 A1 CA2188046 A1 CA 2188046A1
Authority
CA
Canada
Prior art keywords
beneficial agent
fluid
delivering
wall
somatotropin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002188046A
Other languages
French (fr)
Other versions
CA2188046C (en
Inventor
James R. Eckenhoff
Judy A. Magruder
Richard Cortese
Jeremy C. Wright
John R. Peery
James B. Pike
Urano A. Robinson
Jonathan P. Smith
Lyle E. Ziemann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alza Corp
Original Assignee
James R. Eckenhoff
Judy A. Magruder
Richard Cortese
Jeremy C. Wright
John R. Peery
James B. Pike
Urano A. Robinson
Jonathan P. Smith
Lyle E. Ziemann
Eckenhoff, Bonnie J.
Alza Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by James R. Eckenhoff, Judy A. Magruder, Richard Cortese, Jeremy C. Wright, John R. Peery, James B. Pike, Urano A. Robinson, Jonathan P. Smith, Lyle E. Ziemann, Eckenhoff, Bonnie J., Alza Corporation filed Critical James R. Eckenhoff
Publication of CA2188046A1 publication Critical patent/CA2188046A1/en
Application granted granted Critical
Publication of CA2188046C publication Critical patent/CA2188046C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D7/00—Devices or methods for introducing solid, liquid, or gaseous remedies or other materials into or onto the bodies of animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time

Abstract

A delivery system is disclosed for delivering a fluid-sensitive beneficial agent such as a somatotropin, or an analogue or derivative thereof, to an animal such as a bovine. The delivery system comprises a wall that surrounds an internal compartment, said wall comprising a first wall section that limits the passage of fluid into the system and a second wall section that permits the passage of fluid into the system. The wall may further comprise an end cap which may include means for adapting the end cap for ultrasonic welding to the first wall section and means for maintaining the beneficial agent in contact with exit means. The compartment comprises a beneficial agent and an expandable means. The delivery system comprises exit means for delivering the beneficial agent to the animal. The exit means may include means for compensating for slight variations in the efflux rate of the beneficial agent and means for maintaining for a sufficient velocity or efflux rate of beneficial agent outward from the device while minimizing diffusion of fluids from the external environment back into the device.
CA002188046A 1994-07-01 1995-06-30 Osmotic system for delivering of fluid-sensitive somatotropin to bovine animals Expired - Lifetime CA2188046C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/269,596 US5728088A (en) 1988-12-13 1994-07-01 Osmotic system for delivery of fluid-sensitive somatotropins to bovine animals
US08/269,596 1994-07-01
PCT/US1995/008657 WO1996001134A1 (en) 1994-07-01 1995-06-30 Osmotic system for delivering of fluid-sensitive somatotropin to bovine animals

Publications (2)

Publication Number Publication Date
CA2188046A1 true CA2188046A1 (en) 1996-01-18
CA2188046C CA2188046C (en) 2006-06-13

Family

ID=23027923

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002188046A Expired - Lifetime CA2188046C (en) 1994-07-01 1995-06-30 Osmotic system for delivering of fluid-sensitive somatotropin to bovine animals

Country Status (16)

Country Link
US (2) US5728088A (en)
EP (1) EP0767689B1 (en)
JP (1) JP3738033B2 (en)
KR (1) KR100370985B1 (en)
AT (1) ATE180684T1 (en)
AU (1) AU691636B2 (en)
CA (1) CA2188046C (en)
DE (1) DE69510054T2 (en)
ES (1) ES2132693T3 (en)
FI (1) FI117372B (en)
IL (1) IL114399A (en)
NO (1) NO314223B1 (en)
NZ (1) NZ290045A (en)
UY (1) UY23986A1 (en)
WO (1) WO1996001134A1 (en)
ZA (1) ZA955505B (en)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6440457B1 (en) * 1993-05-27 2002-08-27 Alza Corporation Method of administering antidepressant dosage form
US6659977B2 (en) * 1993-10-27 2003-12-09 Schneider (Europe) A.G. Multilayer interventional catheter
US5961765A (en) 1994-09-20 1999-10-05 Schneider (Europe) A. G. Method of making a catheter
US5902605A (en) * 1996-04-18 1999-05-11 Alza Corporation Drug delivery device with minimal residual drug retention
ATE327797T1 (en) 1996-04-26 2006-06-15 Schneider Europ Gmbh INTERVENTION CATHETER
US6165166A (en) 1997-04-25 2000-12-26 Schneider (Usa) Inc. Trilayer, extruded medical tubing and medical devices incorporating such tubing
DE59710866D1 (en) * 1997-08-29 2003-11-20 Schneider Europ Gmbh Buelach Medical catheter
US20020007145A1 (en) 1998-10-23 2002-01-17 Timothy Stivland Catheter having improved bonding region
GB2345010B (en) * 1998-12-17 2002-12-31 Electrosols Ltd A delivery device
US6616652B1 (en) 2000-02-15 2003-09-09 Microsolutions, Inc. Osmotic pump delivery system with pre-hydrated membrane(s) and/or primable catheter
US6464688B1 (en) 2000-02-15 2002-10-15 Microsolutions, Inc. Osmotic pump delivery system with flexible drug compartment
GB0102342D0 (en) * 2001-01-30 2001-03-14 Smithkline Beecham Plc Pharmaceutical formulation
US6632217B2 (en) * 2001-04-19 2003-10-14 Microsolutions, Inc. Implantable osmotic pump
ATE376854T1 (en) * 2002-06-26 2007-11-15 Alza Corp MINIMALLY FORGIVE VOLUME EFFICIENT PISTON FOR OSMOTIC DRUG DELIVERY SYSTEMS
US7731947B2 (en) 2003-11-17 2010-06-08 Intarcia Therapeutics, Inc. Composition and dosage form comprising an interferon particle formulation and suspending vehicle
WO2006083761A2 (en) 2005-02-03 2006-08-10 Alza Corporation Solvent/polymer solutions as suspension vehicles
US11246913B2 (en) 2005-02-03 2022-02-15 Intarcia Therapeutics, Inc. Suspension formulation comprising an insulinotropic peptide
MX2008014870A (en) 2006-05-30 2009-02-12 Intarcia Therapeutics Inc Two-piece, internal-channel osmotic delivery system flow modulator.
CN102274557B (en) 2006-08-09 2014-12-03 精达制药公司 Osmotic delivery systems and piston assemblies
US7538652B2 (en) * 2006-08-29 2009-05-26 International Business Machines Corporation Electrical component tuned by conductive layer deletion
NZ580447A (en) 2007-04-23 2011-06-30 Intarcia Therapeutics Inc Suspension formulations of insulinotropic peptides and uses thereof
US9044542B2 (en) 2007-12-21 2015-06-02 Carticept Medical, Inc. Imaging-guided anesthesia injection systems and methods
US8545440B2 (en) 2007-12-21 2013-10-01 Carticept Medical, Inc. Injection system for delivering multiple fluids within the anatomy
US8002736B2 (en) 2007-12-21 2011-08-23 Carticept Medical, Inc. Injection systems for delivery of fluids to joints
CA2726861C (en) 2008-02-13 2014-05-27 Intarcia Therapeutics, Inc. Devices, formulations, and methods for delivery of multiple beneficial agents
US8216498B2 (en) 2008-09-10 2012-07-10 Boston Scientific Scimed, Inc. Catheter having a coextruded fluoropolymer layer
CA2775676C (en) * 2009-09-28 2016-08-16 Intarcia Therapeutics, Inc. Rapid establishment and/or termination of substantial steady-state drug delivery
US20120208755A1 (en) 2011-02-16 2012-08-16 Intarcia Therapeutics, Inc. Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
US9889085B1 (en) 2014-09-30 2018-02-13 Intarcia Therapeutics, Inc. Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c
CN113598842A (en) 2015-06-03 2021-11-05 因塔西亚制药公司 Implant placement and removal system
EP3458084B1 (en) 2016-05-16 2020-04-01 Intarcia Therapeutics, Inc Glucagon-receptor selective polypeptides and methods of use thereof
USD860451S1 (en) 2016-06-02 2019-09-17 Intarcia Therapeutics, Inc. Implant removal tool
USD840030S1 (en) 2016-06-02 2019-02-05 Intarcia Therapeutics, Inc. Implant placement guide
KR20190104039A (en) 2017-01-03 2019-09-05 인타르시아 세라퓨틱스 인코포레이티드 Methods Including Continuous Administration of GLP-1 Receptor Agonists and Co-administration of Drugs
EP3758647A4 (en) * 2018-02-26 2021-12-08 Argenta Innovation Limited Intra-ruminal device
USD933219S1 (en) 2018-07-13 2021-10-12 Intarcia Therapeutics, Inc. Implant removal tool and assembly
US11529310B2 (en) 2020-12-08 2022-12-20 Ruminant Biotech Corp Limited Devices and methods for delivery of substances to animals

Family Cites Families (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2779241A (en) * 1954-06-18 1957-01-29 Wellington R Howard Elastic action cannon bore scavenger
US3896819A (en) * 1969-04-01 1975-07-29 Alejandro Zaffaroni IUD having a replenishing drug reservoir
US3845761A (en) * 1970-06-02 1974-11-05 Alza Corp Intrauterine contraceptive anti-fertility device for the management of reproduction
US3995631A (en) * 1971-01-13 1976-12-07 Alza Corporation Osmotic dispenser with means for dispensing active agent responsive to osmotic gradient
US3732865A (en) * 1971-01-13 1973-05-15 Alza Corp Osmotic dispenser
US3865108A (en) * 1971-05-17 1975-02-11 Ortho Pharma Corp Expandable drug delivery device
US3845770A (en) * 1972-06-05 1974-11-05 Alza Corp Osmatic dispensing device for releasing beneficial agent
US3916899A (en) * 1973-04-25 1975-11-04 Alza Corp Osmotic dispensing device with maximum and minimum sizes for the passageway
US3995632A (en) * 1973-05-04 1976-12-07 Alza Corporation Osmotic dispenser
US4179337A (en) * 1973-07-20 1979-12-18 Davis Frank F Non-immunogenic polypeptides
US3882233A (en) * 1973-07-27 1975-05-06 American Home Prod Methods of increasing production of pituitary hormones
US4002173A (en) * 1974-07-23 1977-01-11 International Paper Company Diester crosslinked polyglucan hydrogels and reticulated sponges thereof
GB1478759A (en) * 1974-11-18 1977-07-06 Alza Corp Process for forming outlet passageways in pills using a laser
US3987790A (en) * 1975-10-01 1976-10-26 Alza Corporation Osmotically driven fluid dispenser
US4077407A (en) * 1975-11-24 1978-03-07 Alza Corporation Osmotic devices having composite walls
US4063064A (en) * 1976-02-23 1977-12-13 Coherent Radiation Apparatus for tracking moving workpiece by a laser beam
US4203439A (en) * 1976-11-22 1980-05-20 Alza Corporation Osmotic system with volume amplifier for increasing amount of agent delivered therefrom
US4111203A (en) * 1976-11-22 1978-09-05 Alza Corporation Osmotic system with means for improving delivery kinetics of system
US4111202A (en) * 1976-11-22 1978-09-05 Alza Corporation Osmotic system for the controlled and delivery of agent over time
US4207893A (en) * 1977-08-29 1980-06-17 Alza Corporation Device using hydrophilic polymer for delivering drug to biological environment
US4200098A (en) * 1978-10-23 1980-04-29 Alza Corporation Osmotic system with distribution zone for dispensing beneficial agent
US4285987A (en) * 1978-10-23 1981-08-25 Alza Corporation Process for manufacturing device with dispersion zone
US4203440A (en) * 1978-10-23 1980-05-20 Alza Corporation Device having variable volume chamber for dispensing useful agent
US4235236A (en) * 1979-02-12 1980-11-25 Alza Corporation Device for dispensing drug by combined diffusional and osmotic operations
US4320759A (en) * 1980-04-28 1982-03-23 Alza Corporation Dispenser with diffuser
US4309996A (en) * 1980-04-28 1982-01-12 Alza Corporation System with microporous releasing diffusor
US4350271A (en) * 1980-08-22 1982-09-21 Alza Corporation Water absorbing fluid dispenser
US4327725A (en) * 1980-11-25 1982-05-04 Alza Corporation Osmotic device with hydrogel driving member
US4475916A (en) * 1982-03-18 1984-10-09 Merck & Co., Inc. Osmotic drug delivery system
ATE37983T1 (en) * 1982-04-22 1988-11-15 Ici Plc DELAYED RELEASE AGENT.
US4612008A (en) * 1983-05-11 1986-09-16 Alza Corporation Osmotic device with dual thermodynamic activity
US4781714A (en) * 1983-11-02 1988-11-01 Alza Corporation Dispenser for delivering thermo-responsive composition
US4717566A (en) * 1984-03-19 1988-01-05 Alza Corporation Dosage system and method of using same
US4692336A (en) * 1984-03-19 1987-09-08 Alza Corporation Self controlled release device for administering beneficial agent to recipient
US4612186A (en) * 1984-03-19 1986-09-16 Alza Corporation Method for establishing blood levels of biocide in animals
US4652630A (en) * 1985-02-22 1987-03-24 Monsanto Company Method of somatotropin naturation
US4963141A (en) * 1985-08-16 1990-10-16 Alza Corporation Dispensing system for administering beneficial agent formulation to ruminants
US4643731A (en) * 1985-08-16 1987-02-17 Alza Corporation Means for providing instant agent from agent dispensing system
US4599229A (en) * 1985-09-09 1986-07-08 International Minerals & Chemical Corp. Method of promoting animal growth using antibodies against somatostatin
US4765980A (en) * 1986-04-28 1988-08-23 International Minerals & Chemical Corp. Stabilized porcine growth hormone
US4960416A (en) * 1986-04-30 1990-10-02 Alza Corporation Dosage form with improved delivery capability
US4723958A (en) * 1986-05-23 1988-02-09 Merck & Co., Inc. Pulsatile drug delivery system
JP2516922B2 (en) * 1986-07-04 1996-07-24 株式会社日立製作所 Liquid crystal display
US4957494A (en) * 1987-06-25 1990-09-18 Alza Corporation Multi-layer delivery system
US4874388A (en) * 1987-06-25 1989-10-17 Alza Corporation Multi-layer delivery system
US5023088A (en) * 1987-06-25 1991-06-11 Alza Corporation Multi-unit delivery system
NZ226179A (en) * 1987-09-24 1991-04-26 Merck & Co Inc Controlled porosity osmotic pump for sustained release of pharmaceutical agents
US4855141A (en) * 1988-03-25 1989-08-08 Alza Corporation Device comprising means for protecting and dispensing fluid sensitive medicament
US4959218A (en) * 1988-03-25 1990-09-25 Alza Corporation Method for delivering somatotropin to an animal
US5037420A (en) * 1988-12-13 1991-08-06 Alza Corporation Delivery system comprising two sections for delivering somatotropin
US5034229A (en) * 1988-12-13 1991-07-23 Alza Corporation Dispenser for increasing feed conversion of hog
US5135523A (en) * 1988-12-13 1992-08-04 Alza Corporation Delivery system for administering agent to ruminants and swine
US5057318A (en) * 1988-12-13 1991-10-15 Alza Corporation Delivery system for beneficial agent over a broad range of rates
US4969884A (en) * 1988-12-28 1990-11-13 Alza Corporation Osmotically driven syringe
US4976966A (en) * 1988-12-29 1990-12-11 Alza Corporation Delayed release osmotically driven fluid dispenser
GB8915002D0 (en) * 1989-05-16 1989-08-23 Coopers Animal Health Dispensing devices
US5100392A (en) * 1989-12-08 1992-03-31 Biosynthesis, Inc. Implantable device for administration of drugs or other liquid solutions
US5030216A (en) * 1989-12-15 1991-07-09 Alza Corporation Osmotically driven syringe
US5045082A (en) * 1990-01-10 1991-09-03 Alza Corporation Long-term delivery device including loading dose
US5057321A (en) * 1990-06-13 1991-10-15 Alza Corporation Dosage form comprising drug and maltodextrin
US5135123A (en) * 1990-09-20 1992-08-04 Phoenix Closures, Inc. Tamper-evident closure with a separately formed break away band
US5137727A (en) * 1991-06-12 1992-08-11 Alza Corporation Delivery device providing beneficial agent stability
US5223265A (en) * 1992-01-10 1993-06-29 Alza Corporation Osmotic device with delayed activation of drug delivery
US5308348A (en) * 1992-02-18 1994-05-03 Alza Corporation Delivery devices with pulsatile effect
US5209746A (en) * 1992-02-18 1993-05-11 Alza Corporation Osmotically driven delivery devices with pulsatile effect
US5221278A (en) * 1992-03-12 1993-06-22 Alza Corporation Osmotically driven delivery device with expandable orifice for pulsatile delivery effect

Also Published As

Publication number Publication date
FI965284A (en) 1996-12-31
JPH10502285A (en) 1998-03-03
UY23986A1 (en) 1995-12-14
IL114399A0 (en) 1995-10-31
US5728088A (en) 1998-03-17
DE69510054T2 (en) 2000-01-27
FI117372B (en) 2006-09-29
KR100370985B1 (en) 2003-04-11
AU691636B2 (en) 1998-05-21
NO964264L (en) 1997-03-03
ZA955505B (en) 1996-08-14
JP3738033B2 (en) 2006-01-25
CA2188046C (en) 2006-06-13
NO314223B1 (en) 2003-02-17
DE69510054D1 (en) 1999-07-08
ES2132693T3 (en) 1999-08-16
US5980509A (en) 1999-11-09
NO964264D0 (en) 1996-10-08
EP0767689B1 (en) 1999-06-02
FI965284A0 (en) 1996-12-31
NZ290045A (en) 1997-08-22
AU3006395A (en) 1996-01-25
WO1996001134A1 (en) 1996-01-18
ATE180684T1 (en) 1999-06-15
EP0767689A1 (en) 1997-04-16
IL114399A (en) 1999-03-12

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Legal Events

Date Code Title Description
EEER Examination request
MKEX Expiry

Effective date: 20150630