CA2181502A1 - Pharmaceutical preparation in form of coated capsule releasable at lower part of digestive tract - Google Patents

Pharmaceutical preparation in form of coated capsule releasable at lower part of digestive tract

Info

Publication number
CA2181502A1
CA2181502A1 CA002181502A CA2181502A CA2181502A1 CA 2181502 A1 CA2181502 A1 CA 2181502A1 CA 002181502 A CA002181502 A CA 002181502A CA 2181502 A CA2181502 A CA 2181502A CA 2181502 A1 CA2181502 A1 CA 2181502A1
Authority
CA
Canada
Prior art keywords
pharmaceutical preparation
digestive tract
low
polymer film
releasable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002181502A
Other languages
French (fr)
Other versions
CA2181502C (en
Inventor
Harumi Hatano
Takahiro Ito
Takashi Ishibashi
Hiroyuki Yoshino
Masakazu Mizobe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanabe Seiyaku Co Ltd
Original Assignee
Tanabe Seiyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co Ltd filed Critical Tanabe Seiyaku Co Ltd
Publication of CA2181502A1 publication Critical patent/CA2181502A1/en
Application granted granted Critical
Publication of CA2181502C publication Critical patent/CA2181502C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891—Coated capsules; Multilayered drug free capsule shells

Abstract

A pharmaceutical preparation in the form of a coated capsule which can release contents of a capsule at a lower part of the digestive tract comprising (a) a hard capsule containing at least an acidic substance, (b) a polymer film soluble at low pH which is formed on a surface of said hard capsule, and (c) an enteric coating film which is formed on a surface of said polymer film soluble at low pH. According to the pharmaceutical preparation of the present invention, any kind of a medicament can be delivered to any desired site between the upper part of the small intestine and the lower part of the large intestine in the digestive tract by controlling the amount of polymer(s) used for the polymer film soluble at low pH and/or by selecting the kind of the polymer film soluble at low pH and/or the acidic substance without any complicated requirements for each medicament.
CA002181502A 1995-07-20 1996-07-18 Pharmaceutical preparation in form of coated capsule releasable at lower part of digestive tract Expired - Fee Related CA2181502C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP183655/1995 1995-07-20
JP18365595 1995-07-20

Publications (2)

Publication Number Publication Date
CA2181502A1 true CA2181502A1 (en) 1997-01-21
CA2181502C CA2181502C (en) 2003-02-11

Family

ID=16139614

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002181502A Expired - Fee Related CA2181502C (en) 1995-07-20 1996-07-18 Pharmaceutical preparation in form of coated capsule releasable at lower part of digestive tract

Country Status (13)

Country Link
US (1) US6309666B1 (en)
EP (1) EP0754452B1 (en)
KR (1) KR100389602B1 (en)
CN (1) CN1076964C (en)
AT (1) ATE225165T1 (en)
CA (1) CA2181502C (en)
DE (1) DE69624047T2 (en)
DK (1) DK0754452T3 (en)
ES (1) ES2184846T3 (en)
ID (1) ID17428A (en)
PT (1) PT754452E (en)
SG (1) SG80553A1 (en)
TW (1) TW514533B (en)

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WO2012024767A1 (en) * 2010-08-25 2012-03-01 Grant Rufus Sparling Ii Improved enteric active substance delivery

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KR101752080B1 (en) 2007-12-28 2017-06-28 임팩스 라보라토리즈, 인코포레이티드 Controlled release formulations of levodopa and uses thereof
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US10653631B2 (en) 2011-09-07 2020-05-19 Roland SAUR-BROSCH Optimal colon targeting technology
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US10987313B2 (en) 2013-10-07 2021-04-27 Impax Laboratories, Llc Muco-adhesive, controlled release formulations of levodopa and/or esters of levodopa and uses thereof
KR102266091B1 (en) 2013-10-07 2021-06-17 임팩스 라보라토리즈, 인코포레이티드 Muco-adhesive, controlled release formulations of levodopa and/or esters of levodopa and uses thereof
CN108884171B (en) 2016-04-08 2022-02-18 株式会社大赛璐 Cellulose ester and molded article thereof
EP3485879A1 (en) * 2017-11-17 2019-05-22 Maat Pharma Pharmaceutical oral formulation comrpsing bacteria
JP2021528483A (en) * 2018-05-03 2021-10-21 エムダブリュ エンキャップ リミテッド Dosage form for delivery of drug to the lower gastrointestinal tract
JPWO2020071395A1 (en) * 2018-10-02 2021-09-02 クオリカプス株式会社 Hard capsules with improved strength and their manufacturing methods
KR102106244B1 (en) * 2019-10-30 2020-05-04 한국광기술원 Capsule type photodynamic therapy apparatus with anchor
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012024767A1 (en) * 2010-08-25 2012-03-01 Grant Rufus Sparling Ii Improved enteric active substance delivery
US9782354B2 (en) 2010-08-25 2017-10-10 II Grant Rufus Sparling Enteric active substance delivery

Also Published As

Publication number Publication date
DK0754452T3 (en) 2003-02-03
EP0754452A3 (en) 1998-01-21
EP0754452B1 (en) 2002-10-02
CA2181502C (en) 2003-02-11
ES2184846T3 (en) 2003-04-16
US6309666B1 (en) 2001-10-30
CN1142944A (en) 1997-02-19
DE69624047D1 (en) 2002-11-07
SG80553A1 (en) 2001-05-22
MX9602863A (en) 1997-09-30
ID17428A (en) 1997-12-24
DE69624047T2 (en) 2003-08-14
ATE225165T1 (en) 2002-10-15
KR970005279A (en) 1997-02-19
TW514533B (en) 2002-12-21
CN1076964C (en) 2002-01-02
EP0754452A2 (en) 1997-01-22
PT754452E (en) 2003-02-28
KR100389602B1 (en) 2003-09-29

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Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed
MKLA Lapsed

Effective date: 20060718