CA2180659A1 - Use of a collagen membrane in preparation of an implant for guided tissue regeneration - Google Patents

Use of a collagen membrane in preparation of an implant for guided tissue regeneration

Info

Publication number
CA2180659A1
CA2180659A1 CA002180659A CA2180659A CA2180659A1 CA 2180659 A1 CA2180659 A1 CA 2180659A1 CA 002180659 A CA002180659 A CA 002180659A CA 2180659 A CA2180659 A CA 2180659A CA 2180659 A1 CA2180659 A1 CA 2180659A1
Authority
CA
Canada
Prior art keywords
tissue regeneration
membrane
implant
preparation
guided tissue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002180659A
Other languages
French (fr)
Other versions
CA2180659C (en
Inventor
Peter Geistlich
Zdenek Eckmayer
Philip Boyne
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Geistlich Pharma AG
Original Assignee
Peter Geistlich
Zdenek Eckmayer
Philip Boyne
Ed. Geistlich Sohne Ag Fur Chemische Industrie
Geistlich Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10748458&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2180659(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Peter Geistlich, Zdenek Eckmayer, Philip Boyne, Ed. Geistlich Sohne Ag Fur Chemische Industrie, Geistlich Pharma Ag filed Critical Peter Geistlich
Publication of CA2180659A1 publication Critical patent/CA2180659A1/en
Application granted granted Critical
Publication of CA2180659C publication Critical patent/CA2180659C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/34—Shaped forms, e.g. sheets, not provided for in any other sub-group of this main group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/32—Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
    • A61L15/325—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/34—Muscles; Smooth muscle cells; Heart; Cardiac stem cells; Myoblasts; Myocytes; Cardiomyocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/37—Digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A61K35/50—Placenta; Placental stem cells; Amniotic fluid; Amnion; Amniotic stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/28—Polysaccharides or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/40—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing ingredients of undetermined constitution or reaction products thereof, e.g. plant or animal extracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/44—Medicaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/005—Ingredients of undetermined constitution or reaction products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/043—Proteins; Polypeptides; Degradation products thereof
    • A61L31/044—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents

Abstract

The invention relates to a resorbable collagen membrane for use in guided tissue regeneration wherein one face of said membrane is fibrous thereby allowing cell growth thereon and the opposite face of said membrane is smooth, thereby inhibiting cell adhesion thereon. Such a membrane is of particular use in the treatment of wounds and lesions.
CA002180659A 1994-01-06 1995-01-04 Use of a collagen membrane in preparation of an implant for guided tissue regeneration Expired - Lifetime CA2180659C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9400163.3 1994-01-06
GB9400163A GB9400163D0 (en) 1994-01-06 1994-01-06 Membrane
PCT/GB1995/000008 WO1995018638A1 (en) 1994-01-06 1995-01-04 Membrane

Publications (2)

Publication Number Publication Date
CA2180659A1 true CA2180659A1 (en) 1995-07-13
CA2180659C CA2180659C (en) 2006-11-21

Family

ID=10748458

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002180659A Expired - Lifetime CA2180659C (en) 1994-01-06 1995-01-04 Use of a collagen membrane in preparation of an implant for guided tissue regeneration

Country Status (9)

Country Link
US (1) US5837278A (en)
EP (2) EP0738161B1 (en)
JP (1) JP3577083B2 (en)
AT (1) ATE314102T1 (en)
CA (1) CA2180659C (en)
DE (1) DE69534713T2 (en)
ES (2) ES2400947T3 (en)
GB (1) GB9400163D0 (en)
WO (1) WO1995018638A1 (en)

Families Citing this family (154)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9503492D0 (en) * 1995-02-22 1995-04-12 Ed Geistlich S Hne A G F R Che Chemical product
GB9721585D0 (en) * 1997-10-10 1997-12-10 Geistlich Soehne Ag Chemical product
US20030039695A1 (en) * 2001-08-10 2003-02-27 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Collagen carrier of therapeutic genetic material, and method
US20050186673A1 (en) * 1995-02-22 2005-08-25 Ed. Geistlich Soehne Ag Fuer Chemistrie Industrie Collagen carrier of therapeutic genetic material, and method
US7141072B2 (en) 1998-10-05 2006-11-28 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Method for promoting regeneration of surface cartilage in a damaged joint using multi-layer covering
JPH09122225A (en) * 1995-10-31 1997-05-13 Bio Eng Lab:Kk Raw membrane material for medical material and manufacture thereof
JPH09122227A (en) * 1995-10-31 1997-05-13 Bio Eng Lab:Kk Medical material and manufacture thereof
JP3476631B2 (en) * 1995-12-21 2003-12-10 株式会社アムニオテック Medical material composed of human-derived natural collagen membrane
US6352558B1 (en) 1996-02-22 2002-03-05 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Method for promoting regeneration of surface cartilage in a damage joint
DE19654884C2 (en) * 1996-03-04 1999-07-29 Kirsch Axel Molded body
US5940807A (en) * 1996-05-24 1999-08-17 Purcell; Daniel S. Automated and independently accessible inventory information exchange system
US20020173806A1 (en) * 1996-08-30 2002-11-21 Verigen Transplantation Service International (Vtsi) Ag Method for autologous transplantation
US6569172B2 (en) 1996-08-30 2003-05-27 Verigen Transplantation Service International (Vtsi) Method, instruments, and kit for autologous transplantation
US20060025786A1 (en) * 1996-08-30 2006-02-02 Verigen Transplantation Service International (Vtsi) Ag Method for autologous transplantation
US5989269A (en) 1996-08-30 1999-11-23 Vts Holdings L.L.C. Method, instruments and kit for autologous transplantation
TW501934B (en) * 1996-11-20 2002-09-11 Tapic Int Co Ltd Collagen material and process for making the same
GB9716219D0 (en) * 1997-07-31 1997-10-08 Geistlich Soehne Ag Prevention of metastases
US8304390B2 (en) 1997-07-31 2012-11-06 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Method of treatment for preventing or reducing tumor growth in the liver of patient
FR2766716B1 (en) 1997-08-01 2000-02-18 Cogent Sarl COMPOSITE PROSTHESIS FOR PREVENTION OF POST-SURGICAL ADHESIONS AND PROCESS FOR OBTAINING SAME
FR2766717B1 (en) 1997-08-01 2000-06-09 Cogent Sarl COMPOSITE PROSTHESIS FOR PREVENTION OF POST-SURGICAL ADHESIONS AND PROCESS FOR OBTAINING SAME
US6468519B1 (en) * 1997-09-10 2002-10-22 Rutgers, The State University Of New Jersey Polyanhydrides with biologically active degradation products
US7122615B1 (en) * 1998-09-10 2006-10-17 Rutgers, The State University Of New Jersey Polyanhydrides with therapeutically useful degradation products
US6486214B1 (en) * 1997-09-10 2002-11-26 Rutgers, The State University Of New Jersey Polyanhydride linkers for production of drug polymers and drug polymer compositions produced thereby
US20030180263A1 (en) 2002-02-21 2003-09-25 Peter Geistlich Resorbable extracellular matrix for reconstruction of bone
US20050186283A1 (en) * 1997-10-10 2005-08-25 Ed. Geistlich Soehne Ag Fuer Chemistrie Industrie Collagen carrier of therapeutic genetic material, and method
US9034315B2 (en) 1997-10-10 2015-05-19 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Cell-charged multi-layer collagen membrane
US8858981B2 (en) * 1997-10-10 2014-10-14 Ed. Geistlich Soehne Fuer Chemistrie Industrie Bone healing material comprising matrix carrying bone-forming cells
AU1655899A (en) * 1997-12-10 1999-06-28 Douglas Alan Schappert Integrated guided-tissue-regeneration barrier for root-form dental implants
US20050208114A1 (en) * 1998-03-24 2005-09-22 Petito George D Composition and method for healing tissues
US7691829B2 (en) * 1998-03-24 2010-04-06 Petito George D Composition and method for healing tissues
TR200200088T2 (en) * 1998-08-14 2002-06-21 Verigen Transplantation Service International (Vtsi) Ag Methods for chondrocyte cell transplantation; instruments and substances
US6977231B1 (en) 1999-01-21 2005-12-20 Nipro Corporation Suturable adhesion-preventing membrane
US20020102709A1 (en) * 1999-02-19 2002-08-01 Tetsuya Ishikawa Collagen-binding physiologically active polypeptide
US7892530B2 (en) 1999-06-04 2011-02-22 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Treatment of tumor metastases and cancer
US7345039B2 (en) 1999-06-04 2008-03-18 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Enhancement of effectiveness of 5-fluorouracil in treatment of tumor metastases and cancer
US8030301B2 (en) 1999-06-04 2011-10-04 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Treatment of cancers with methylol-containing compounds and at least one electrolyte
US20020116063A1 (en) * 1999-08-02 2002-08-22 Bruno Giannetti Kit for chondrocyte cell transplantation
US6312474B1 (en) 1999-09-15 2001-11-06 Bio-Vascular, Inc. Resorbable implant materials
US6221109B1 (en) * 1999-09-15 2001-04-24 Ed. Geistlich Söhne AG fur Chemische Industrie Method of protecting spinal area
EP1797884B1 (en) * 1999-12-06 2013-09-11 Geistlich Pharma AG Taurolidine or taurultam for use in the treatment of tumors of the prostate, colon, lung and for the treatment of recurrent glioblastoma multiforme
US20040038948A1 (en) 1999-12-07 2004-02-26 Uhrich Kathryn E. Therapeutic compositions and methods
ATE444086T1 (en) 1999-12-07 2009-10-15 Univ Rutgers THERAPEUTIC COMPOSITIONS AND METHODS FOR TREATING PERIODONTITIS WITH ANTI-INFLAMMATORY AGENTS
US6685928B2 (en) 1999-12-07 2004-02-03 Rutgers, The State University Of New Jersey Therapeutic compositions and methods
US6623963B1 (en) 1999-12-20 2003-09-23 Verigen Ag Cellular matrix
US6641571B2 (en) 2000-01-05 2003-11-04 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Reduction of postoperative complications of cardiopulmonary bypass (CPB) surgery
US6682760B2 (en) 2000-04-18 2004-01-27 Colbar R&D Ltd. Cross-linked collagen matrices and methods for their preparation
JP3865635B2 (en) * 2000-05-26 2007-01-10 エンゲルハード・リヨン Collagen-based supports for tissue engineering and biomaterial manufacturing
CZ301649B6 (en) * 2000-06-28 2010-05-12 Ed. Geistlich Soehne Ag Fur Chemische Industrie Incorporated Under The Laws Of Switzerland Tube for regeneration of nerves and process for producing thereof
DK177997B1 (en) 2000-07-19 2015-02-23 Ed Geistlich Söhne Ag Für Chemische Ind Bone material and collagen combination for healing of damaged joints
IT1318663B1 (en) * 2000-08-02 2003-08-27 Mediolanum Farmaceutici Srl TWO-SIDED COLLAGEN MEMBRANES, ONE OF WHICH ORGANIZED AT THE MACRO-MOLECULAR LEVEL.
CA2365376C (en) 2000-12-21 2006-03-28 Ethicon, Inc. Use of reinforced foam implants with enhanced integrity for soft tissue repair and regeneration
CA2438047A1 (en) * 2001-02-14 2002-08-22 Hildegard M. Kramer Biocompatible fleece for hemostasis and tissue engineering
US6713085B2 (en) * 2001-04-27 2004-03-30 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Method and membrane for mucosa regeneration
US6444222B1 (en) * 2001-05-08 2002-09-03 Verigen Transplantation Services International Ag Reinforced matrices
JP2003160506A (en) * 2001-08-10 2003-06-03 Ed Geistlich Soehne Ag Fuer Chemische Industrie Collagen carrier of therapeutic genetic material and method
CA2412012C (en) 2001-11-20 2011-08-02 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Resorbable extracellular matrix containing collagen i and collagen ii for reconstruction of cartilage
US20030187515A1 (en) 2002-03-26 2003-10-02 Hariri Robert J. Collagen biofabric and methods of preparing and using the collagen biofabric
US7166133B2 (en) 2002-06-13 2007-01-23 Kensey Nash Corporation Devices and methods for treating defects in the tissue of a living being
AU2003251992A1 (en) * 2002-07-17 2004-02-02 Rutgers, The State University Therapeutic devices for patterned cell growth
US20040136968A1 (en) * 2002-09-27 2004-07-15 Verigen Ag Autologous cells on a support matrix for tissue repair
US20040078090A1 (en) 2002-10-18 2004-04-22 Francois Binette Biocompatible scaffolds with tissue fragments
US7144588B2 (en) 2003-01-17 2006-12-05 Synovis Life Technologies, Inc. Method of preventing surgical adhesions
EP2450065B1 (en) 2003-02-06 2017-08-23 CellSeed Inc. Corneal epithelium forming cell sheets, processes for producing the same, and methods of using the same
US8197837B2 (en) 2003-03-07 2012-06-12 Depuy Mitek, Inc. Method of preparation of bioabsorbable porous reinforced tissue implants and implants thereof
US7368124B2 (en) * 2003-03-07 2008-05-06 Depuy Mitek, Inc. Method of preparation of bioabsorbable porous reinforced tissue implants and implants thereof
US8226715B2 (en) 2003-06-30 2012-07-24 Depuy Mitek, Inc. Scaffold for connective tissue repair
US10583220B2 (en) 2003-08-11 2020-03-10 DePuy Synthes Products, Inc. Method and apparatus for resurfacing an articular surface
US7296998B2 (en) * 2003-09-22 2007-11-20 Bartee Chaddick M Hydrophilic high density PTFE medical barrier
DE10349722A1 (en) 2003-10-23 2005-06-16 Beschorner, Katharina, Dr. Composition for arthritis / arthritis treatment, in particular of joints
US11395865B2 (en) 2004-02-09 2022-07-26 DePuy Synthes Products, Inc. Scaffolds with viable tissue
JP5008396B2 (en) * 2004-04-30 2012-08-22 サンスター スイス エスエー Biocompatible membrane and method for producing the same
CN100372576C (en) * 2004-12-29 2008-03-05 东华大学 Composite collagen nerve ductus for promoting neural regeneration, and method for forming filature from hollow wet process
AU2006265601A1 (en) * 2005-06-30 2007-01-11 Anthrogenesis Corporation Repair of tympanic membrane using placenta derived collagen biofabric
CN101252948A (en) * 2005-09-02 2008-08-27 埃德盖斯特利希索恩化学工业股份公司 Method of repairing meniscus tears
WO2007049125A1 (en) * 2005-10-24 2007-05-03 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Method and device for synovial cell-charged collagen membrane or gel
PT1842568E (en) * 2006-04-05 2008-09-22 Opocrin Spa Multimicrolamellar collagen membranes
US20080026032A1 (en) * 2006-07-27 2008-01-31 Zubery Yuval Composite implants for promoting bone regeneration and augmentation and methods for their preparation and use
WO2008021391A1 (en) * 2006-08-15 2008-02-21 Anthrogenesis Corporation Umbilical cord biomaterial for medical use
CN101528195B (en) * 2006-09-07 2012-03-28 埃德盖斯特利希索恩化学工业股份公司 Use of hydroxymethyl transferring agent in preparing medicine for treating bone cancer
WO2008034019A2 (en) 2006-09-13 2008-03-20 Polymerix Corporation Active agents and their oligomers and polymers
US20080131522A1 (en) * 2006-10-03 2008-06-05 Qing Liu Use of placental biomaterial for ocular surgery
US8071135B2 (en) 2006-10-04 2011-12-06 Anthrogenesis Corporation Placental tissue compositions
CN104623643A (en) 2006-10-06 2015-05-20 人类起源公司 Natural (telopeptide) placental collagen compositions
PT2097116E (en) 2006-12-22 2012-12-06 Medidom Lab In situ system for intra-articular chondral and osseous tissue repair
US9056151B2 (en) 2007-02-12 2015-06-16 Warsaw Orthopedic, Inc. Methods for collagen processing and products using processed collagen
US9308068B2 (en) 2007-12-03 2016-04-12 Sofradim Production Implant for parastomal hernia
CN104491845A (en) 2008-04-18 2015-04-08 科尔普兰特有限公司 Methods Of Generating And Using Procollagen
US9358320B2 (en) 2008-04-25 2016-06-07 Allosource Multi-layer tissue patches
US9480549B2 (en) 2008-04-25 2016-11-01 Allosource Multi-layer tissue patches
US9242026B2 (en) 2008-06-27 2016-01-26 Sofradim Production Biosynthetic implant for soft tissue repair
US9770538B2 (en) * 2009-01-16 2017-09-26 Geistlich Pharma Ag Method and membrane for skin regeneration
FR2949688B1 (en) 2009-09-04 2012-08-24 Sofradim Production FABRIC WITH PICOTS COATED WITH A BIORESORBABLE MICROPOROUS LAYER
US20140286911A1 (en) 2013-03-15 2014-09-25 Allosource Cell repopulated collagen matrix for soft tissue repair and regeneration
EP2549957B1 (en) 2010-03-23 2019-01-30 Edwards Lifesciences Corporation Methods of conditioning sheet bioprosthetic tissue
US8460691B2 (en) 2010-04-23 2013-06-11 Warsaw Orthopedic, Inc. Fenestrated wound repair scaffold
US8790699B2 (en) 2010-04-23 2014-07-29 Warsaw Orthpedic, Inc. Foam-formed collagen strand
US8951598B2 (en) 2010-05-07 2015-02-10 Empire Technology Development Llc Nanoscale collagen particles and membranes
US8741317B2 (en) 2010-08-19 2014-06-03 Rutgers, The State University Of New Jersey Slow-degrading polymers comprising salicylic acid for undelayed and sustained drug delivery
WO2012116372A1 (en) 2011-02-25 2012-08-30 Rosen Richard A Biomaterials for soft and hard tissue repair
FR2972626B1 (en) 2011-03-16 2014-04-11 Sofradim Production PROSTHETIC COMPRISING A THREE-DIMENSIONAL KNIT AND ADJUSTED
CN102225219B (en) * 2011-06-01 2014-01-29 陕西博鸿生物科技有限公司 Bone tissue regeneration guiding membrane and preparation method thereof
FR2977789B1 (en) 2011-07-13 2013-07-19 Sofradim Production PROSTHETIC FOR UMBILIC HERNIA
FR2977790B1 (en) 2011-07-13 2013-07-19 Sofradim Production PROSTHETIC FOR UMBILIC HERNIA
EP2760494B1 (en) 2011-09-30 2017-04-19 Sofradim Production Reversible stiffening of light weight mesh
US9162011B2 (en) 2011-12-19 2015-10-20 Allosource Flowable matrix compositions and methods
FR2985271B1 (en) 2011-12-29 2014-01-24 Sofradim Production KNITTED PICOTS
FR2985170B1 (en) 2011-12-29 2014-01-24 Sofradim Production PROSTHESIS FOR INGUINAL HERNIA
US10071184B2 (en) 2012-02-29 2018-09-11 Collagen Matrix, Inc. Collagen-coated tissue-based membranes
EP2674166A1 (en) * 2012-06-15 2013-12-18 Universitätsmedizin der Johannes Gutenberg-Universität Mainz Use of erythropoietin (EPO) for the local treatment of cancer treatment-associated osteo-necrosis of the jaw
KR101455837B1 (en) * 2012-07-09 2014-11-03 주식회사 오스코텍 Process for preparing resorbable barrier membrane for guided tissue regeneration
US9644177B2 (en) * 2012-07-12 2017-05-09 Board Of Regents, The University Of Texas System Extracellular matrix films and methods of making and using same
FR2994185B1 (en) 2012-08-02 2015-07-31 Sofradim Production PROCESS FOR THE PREPARATION OF A POROUS CHITOSAN LAYER
US9144579B2 (en) 2012-08-17 2015-09-29 Rutgers, The State University Of New Jersey Polyesters and methods of use thereof
FR2995779B1 (en) 2012-09-25 2015-09-25 Sofradim Production PROSTHETIC COMPRISING A TREILLIS AND A MEANS OF CONSOLIDATION
FR2995788B1 (en) 2012-09-25 2014-09-26 Sofradim Production HEMOSTATIC PATCH AND PREPARATION METHOD
FR2995778B1 (en) 2012-09-25 2015-06-26 Sofradim Production ABDOMINAL WALL REINFORCING PROSTHESIS AND METHOD FOR MANUFACTURING THE SAME
AU2013322268B2 (en) 2012-09-28 2017-08-31 Sofradim Production Packaging for a hernia repair device
US20140120057A1 (en) 2012-10-25 2014-05-01 Rutgers, The State University Of New Jersey Polymers and methods thereof for wound healing
KR101434041B1 (en) 2012-11-08 2014-08-29 주식회사 제네웰 and method of preparing membrane for leading regeneration produced from material derived from biological tissue
CN103961752B (en) * 2013-02-02 2016-01-20 深圳兰度生物材料有限公司 Tissue regeneration guiding film and preparation method thereof
WO2014164900A1 (en) 2013-03-13 2014-10-09 Allosource Fascia fibrous compositions and methods for their use and manufacture
US9387250B2 (en) 2013-03-15 2016-07-12 Rutgers, The State University Of New Jersey Therapeutic compositions for bone repair
WO2014194055A1 (en) 2013-05-29 2014-12-04 Rutgers, The State University Of New Jersey Antioxidant-based poly(anhydride-esters)
FR3006581B1 (en) 2013-06-07 2016-07-22 Sofradim Production PROSTHESIS BASED ON TEXTILE FOR LAPAROSCOPIC PATHWAY
FR3006578B1 (en) 2013-06-07 2015-05-29 Sofradim Production PROSTHESIS BASED ON TEXTILE FOR LAPAROSCOPIC PATHWAY
EP2826495A1 (en) 2013-07-19 2015-01-21 Geistlich Pharma AG Biomimetic collagen-hydroxyapatite composite material
EP2842515A1 (en) 2013-08-29 2015-03-04 nolax AG Diaphragm, operation set with diaphragm and method for applying a diaphragm
WO2015085232A1 (en) 2013-12-06 2015-06-11 Allosource Method of drying sheets of tissue
US10023521B2 (en) 2014-06-13 2018-07-17 Rutgers, The State University Of New Jersey Process and intermediates for preparing poly(anhydride-esters)
EP3000489B1 (en) 2014-09-24 2017-04-05 Sofradim Production Method for preparing an anti-adhesion barrier film
EP3000433B1 (en) 2014-09-29 2022-09-21 Sofradim Production Device for introducing a prosthesis for hernia treatment into an incision and flexible textile based prosthesis
EP3000432B1 (en) 2014-09-29 2022-05-04 Sofradim Production Textile-based prosthesis for treatment of inguinal hernia
EP3029189B1 (en) 2014-12-05 2021-08-11 Sofradim Production Prosthetic porous knit, method of making same and hernia prosthesis
EP3034103A1 (en) 2014-12-15 2016-06-22 Geistlich Pharma AG Collagen Sponge
EP3059255B1 (en) 2015-02-17 2020-05-13 Sofradim Production Method for preparing a chitosan-based matrix comprising a fiber reinforcement member
WO2016164898A1 (en) 2015-04-10 2016-10-13 Rutgers, The State University Of New Jersey Kojic acid polymers
EP3085337B1 (en) 2015-04-24 2022-09-14 Sofradim Production Prosthesis for supporting a breast structure
WO2016186594A1 (en) * 2015-05-20 2016-11-24 SUNAL, Elif A barrier membrane used in periodontitis treatment and a production method thereof
ES2676072T3 (en) 2015-06-19 2018-07-16 Sofradim Production Synthetic prosthesis comprising a knitted fabric and a non-porous film and method of forming it
EP3175869A1 (en) 2015-12-04 2017-06-07 Geistlich Pharma AG Resorbable crosslinked formstable membrane
IL243401A (en) 2015-12-29 2017-12-31 Zion Karmon Ben Devices and methods for elevating the schneiderian membrane
EP3195830B1 (en) 2016-01-25 2020-11-18 Sofradim Production Prosthesis for hernia repair
IL248472A0 (en) 2016-10-13 2017-01-31 Zion Karmon Ben Devices for tissue regeneration
EP3312325B1 (en) 2016-10-21 2021-09-22 Sofradim Production Method for forming a mesh having a barbed suture attached thereto and the mesh thus obtained
US10772986B2 (en) 2017-01-26 2020-09-15 Allosource Fascia fibrous compositions and methods for their use and manufacture
EP3398554A1 (en) 2017-05-02 2018-11-07 Sofradim Production Prosthesis for inguinal hernia repair
EP3409303A1 (en) 2017-06-02 2018-12-05 Geistlich Pharma AG Use of a resorbable crosslinked form stable composition for preparing a membrane
IL275206B2 (en) 2017-12-14 2023-04-01 Geistlich Pharma Ag Dried implant composition and injectable aqueous implant formulation
EP3653171A1 (en) 2018-11-16 2020-05-20 Sofradim Production Implants suitable for soft tissue repair
US10869949B2 (en) 2019-04-11 2020-12-22 Geistlich Pharma Ag Method for treating subjects suffering from chronic ulcers
US11357891B2 (en) * 2019-06-14 2022-06-14 Geistlich Pharma Ag Collagen matrix or granulate blend of bone substitute material
AU2020292778B2 (en) 2019-06-14 2022-08-11 Geistlich Pharma Ag Injectable aqueous implant formulation containing ascorbic acid
ES2939266T3 (en) 2019-06-14 2023-04-20 Geistlich Pharma Ag Collagen matrix or granulated mixture of bone substitute material
EP4209232A1 (en) 2022-01-06 2023-07-12 Geistlich Pharma AG Collagen device for meniscus regeneration

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2517452C3 (en) * 1975-04-19 1978-11-02 Fa. Carl Freudenberg, 6940 Weinheim Collagen foil for cosmetic use
US4060081A (en) 1975-07-15 1977-11-29 Massachusetts Institute Of Technology Multilayer membrane useful as synthetic skin
US4185011A (en) * 1978-10-16 1980-01-22 Firma Carl Freudenberg Process for the production of collagen fibers
US4292972A (en) * 1980-07-09 1981-10-06 E. R. Squibb & Sons, Inc. Lyophilized hydrocolloio foam
DE3203957A1 (en) * 1982-02-05 1983-08-18 Chemokol Gesellschaft zur Entwicklung von Kollagenprodukten, 5190 Stolberg Method for the production of fine-pore collagen sponges
US4600533A (en) * 1984-12-24 1986-07-15 Collagen Corporation Collagen membranes for medical use
US4674488A (en) * 1985-03-04 1987-06-23 American Hospital Supply Corporation Method of treating bone fractures to reduce formation of fibrous adhesions
WO1988008305A1 (en) 1987-04-28 1988-11-03 The Regents Of The University Of California Method and apparatus for preparing composite skin replacement
ATE109491T1 (en) * 1988-03-11 1994-08-15 Chemokol G B R Ing Buero Fuer PROCESS FOR MANUFACTURING COLLAGEN MEMBRANES FOR HEMOSTASIS, WOUND TREATMENT AND IMPLANTS.
US5573771A (en) * 1988-08-19 1996-11-12 Osteomedical Limited Medicinal bone mineral products
WO1990013302A1 (en) * 1989-04-28 1990-11-15 Brigham And Women's Hospital Novel materials and methods for guided tissue regeneration
FR2679778B1 (en) * 1991-08-02 1995-07-07 Coletica USE OF CROLAGEN CROSSLINKED BY A CROSSLINKING AGENT FOR THE MANUFACTURE OF A SLOW RESORPTIVE, BIOCOMPATIBLE, SUTURABLE MEMBRANE, AS WELL AS SUCH A MEMBRANE.
WO1993010722A2 (en) * 1991-11-26 1993-06-10 Research Development Foundation Fetal membrane tubes for nerve and vessel grafts

Also Published As

Publication number Publication date
ATE314102T1 (en) 2006-01-15
DE69534713D1 (en) 2006-02-02
WO1995018638A1 (en) 1995-07-13
ES2255707T3 (en) 2006-07-01
CA2180659C (en) 2006-11-21
US5837278A (en) 1998-11-17
JP3577083B2 (en) 2004-10-13
EP1676592A1 (en) 2006-07-05
EP0738161A1 (en) 1996-10-23
EP0738161B1 (en) 2005-12-28
ES2400947T3 (en) 2013-04-15
EP1676592B1 (en) 2013-01-23
JPH09507144A (en) 1997-07-22
GB9400163D0 (en) 1994-03-02
DE69534713T2 (en) 2006-07-06

Similar Documents

Publication Publication Date Title
CA2180659A1 (en) Use of a collagen membrane in preparation of an implant for guided tissue regeneration
EP2338448A3 (en) Anti-inflammatory and antimicrobial uses for bioactive glass
CA2155319A1 (en) Multilayer nonwoven tissue containing a surface layer comprising at least one hyaluronic acid ester
CA2234235A1 (en) Gel formulations containing growth factors
CA2241188A1 (en) Hydrogel wound dressing and the method of making and using the same
CA2097244A1 (en) Method for treating bioabsorbable implant material
CA2188563A1 (en) Stent with collagen
CA2126087A1 (en) Composite membranes for the guided regeneration of tissues
CA2197258A1 (en) Surgical suture
RU94030735A (en) COMPOSITION MEMBRANE, METHOD FOR ITS PREPARATION AND METHOD FOR DIRECTED TISSUE REGENERATION WITH ITS APPLICATION
AU2676795A (en) Soft implantable surgical prosthesis for increasing or restoring the volume of soft tissues, in particular a breast prosthesis and method of manufacture
AU6596094A (en) Antibacterial vascular prosthesis and surgical suture
CA2183263A1 (en) Improved process for fixation of calcification-resistant biological tissue
CA2135999A1 (en) Biotherapeutic Cell-Coated Microspheres
CA2305740A1 (en) Membrane for use in guided tissue regeneration
AU2154700A (en) Systems for securing sutures, grafts and soft tissue to bone and periosteum
ES8801111A1 (en) A biomaterial comprising a composite material of chitosan derivative and collagen and a process for the production of the same.
AU4730096A (en) Living tissue implant with electrical transponder
CA2014542A1 (en) Medical implant and method for the manufacture thereof
TW347318B (en) Wound dressing
CA2130762A1 (en) Treatment of Disease and Conditions Associated with Macrophage Infiltration
GB9708692D0 (en) Dermal sheath tissue and/or cells derived therefrom in wound healing
AU3162895A (en) Membrane for regenerating body tissues and use of said membrane as a wound covering and substitute skin
EP1736170A3 (en) Agent for treating allergic or hypersensitivity condition
PL336662A1 (en) Tissular factor producing a blood vesell formation effect

Legal Events

Date Code Title Description
EEER Examination request
MKEX Expiry

Effective date: 20150105