CA2132826A1 - Use of Borate-Polyol Complexes in Ophthalmic Compositions - Google Patents

Use of Borate-Polyol Complexes in Ophthalmic Compositions

Info

Publication number
CA2132826A1
CA2132826A1 CA 2132826 CA2132826A CA2132826A1 CA 2132826 A1 CA2132826 A1 CA 2132826A1 CA 2132826 CA2132826 CA 2132826 CA 2132826 A CA2132826 A CA 2132826A CA 2132826 A1 CA2132826 A1 CA 2132826A1
Authority
CA
Canada
Prior art keywords
borate
ophthalmic compositions
polyol complexes
complexes
polyvinyl alcohol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA 2132826
Other languages
French (fr)
Other versions
CA2132826C (en
Inventor
Masood Chowhan
Nissanke Lakshman Dassanayake
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alcon Vision LLC
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25374152&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2132826(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Individual filed Critical Individual
Publication of CA2132826A1 publication Critical patent/CA2132826A1/en
Application granted granted Critical
Publication of CA2132826C publication Critical patent/CA2132826C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

Aqueous ophthalmic compositions containing water-soluble borate-polyol complexes are useful in aqueous ophthalmic compositions containing polyvinyl alcohol. These compositions provide the benefits of a borate buffering system, such as enhanced antimicrobial activity, without the problems associated with the use of borate and pol, such as formation of borate-polyvinyl alcohol complexes which are water-insoluble.
CA002132826A 1992-05-06 1993-05-04 Use of borate-polyol complexes in ophthalmic compositions Expired - Lifetime CA2132826C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US87943592A 1992-05-06 1992-05-06
US879,435 1992-05-06

Publications (2)

Publication Number Publication Date
CA2132826A1 true CA2132826A1 (en) 1993-11-11
CA2132826C CA2132826C (en) 1999-01-05

Family

ID=25374152

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002132826A Expired - Lifetime CA2132826C (en) 1992-05-06 1993-05-04 Use of borate-polyol complexes in ophthalmic compositions

Country Status (11)

Country Link
US (1) US5342620A (en)
EP (1) EP0639070B2 (en)
JP (2) JP3337218B2 (en)
AT (1) ATE300936T1 (en)
AU (1) AU674852B2 (en)
CA (1) CA2132826C (en)
DE (1) DE69333850T3 (en)
DK (1) DK0639070T4 (en)
ES (1) ES2246491T5 (en)
HK (1) HK1011615A1 (en)
WO (1) WO1993021903A1 (en)

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KR20080033939A (en) * 2005-06-17 2008-04-17 리지너크스 바이오 파마소티컬스, 인코포레이티드 Lkktet and/or lkktnt peptide compositions which are lyophilized or in a form capable of being lyophilized
US20070297990A1 (en) * 2006-06-27 2007-12-27 Shah Mandar V Self-preserving composition
TWI394564B (en) * 2006-09-21 2013-05-01 Alcon Res Ltd Self-preserved aqueous pharmaceutical compositions
US8388941B2 (en) 2006-09-28 2013-03-05 Alcon Research, Ltd. Self preserved aqueous pharmaceutical compositions
JP2008094780A (en) * 2006-10-13 2008-04-24 Nippon Tenganyaku Kenkyusho:Kk Aqueous ophthalmic preparation of levobunolol hydrochloride
US8138156B2 (en) * 2006-10-18 2012-03-20 Bausch & Lomb Incorporated Ophthalmic compositions containing diglycine
US20080110770A1 (en) * 2006-11-10 2008-05-15 Bausch & Lomb Incorporated Packaging solutions
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US8629099B2 (en) * 2008-03-25 2014-01-14 Bausch & Lomb Incorporated Ophthalmic compositions comprising a dipeptide
TWI454289B (en) * 2008-04-03 2014-10-01 Alcon Res Ltd Use of cis-diol-containing polymer to inhibit the uptake of cationic biocides into hydrogel biomaterials
TWI544934B (en) * 2008-06-09 2016-08-11 愛爾康研究有限公司 Improved pharmaceutical compositions containing a fluoroquinolone antibiotic drug
US8093352B2 (en) * 2008-08-05 2012-01-10 Alcon Research, Ltd. Polyalkylene oxide polyquaternary ammonium biocides
US8431751B1 (en) 2008-12-24 2013-04-30 Alcon Research, Ltd. Polymeric quaternary ammonium compounds with vicinal hydroxy groups
TW201038295A (en) 2009-04-17 2010-11-01 Alcon Res Ltd Aqueous ophthalmic compositions containing anionic therapeutic agents
TWI489997B (en) * 2009-06-19 2015-07-01 Alcon Res Ltd Aqueous pharmaceutical compositions containing borate-polyol complexes
TWI547522B (en) * 2009-07-07 2016-09-01 愛爾康研究有限公司 Ethyleneoxide butyleneoxide block copolymer compositions
WO2011153349A1 (en) 2010-06-02 2011-12-08 Alcon Research, Ltd. Ophthalmic compositions comprising pbo-peo-pbo block copolymers
JP5870459B2 (en) 2010-08-27 2016-03-01 わかもと製薬株式会社 Aqueous composition for eye drops
TWI544922B (en) 2011-05-19 2016-08-11 愛爾康研究有限公司 High concentration olopatadine ophthalmic composition
JP2013129618A (en) * 2011-12-21 2013-07-04 Nippon Tenganyaku Kenkyusho:Kk Levofloxacin-containing water liquid medicine that improves antiseptic efficacy and physical properties
US8324171B1 (en) 2012-02-06 2012-12-04 Bausch & Lomb Incorporated Ophthalmic compositions containing diglycine
US8664180B2 (en) 2012-02-06 2014-03-04 Bausch & Lomb Incorporated Ophthalmic compositions containing diglycine
WO2019191200A1 (en) 2018-03-27 2019-10-03 American Genomics, Llc Method and formulation for producing anesthesia of internal aspect of eye wall by topical application
CN113056199A (en) 2018-11-08 2021-06-29 陈煌兴 Trisubstituted biguanide compounds and uses thereof
AU2020245203A1 (en) * 2019-03-26 2021-11-11 Martin Uram Anesthetic composition and method of anesthetizing the eye
PT3769753T (en) * 2019-07-23 2022-02-15 Nicox Ophthalmics Inc Process for the preparation of sterile ophthalmic aqueous fluticasone propionate form a nanocrystals suspensions
CN117813116A (en) * 2021-08-06 2024-04-02 株式会社大塚制药工场 Disinfecting composition

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Also Published As

Publication number Publication date
JPH07506377A (en) 1995-07-13
JP2002177369A (en) 2002-06-25
WO1993021903A1 (en) 1993-11-11
DK0639070T4 (en) 2010-12-13
AU674852B2 (en) 1997-01-16
DK0639070T3 (en) 2005-11-28
ES2246491T5 (en) 2011-01-31
EP0639070B2 (en) 2010-09-08
US5342620A (en) 1994-08-30
EP0639070B1 (en) 2005-08-03
ATE300936T1 (en) 2005-08-15
JP3337218B2 (en) 2002-10-21
HK1011615A1 (en) 1999-07-16
CA2132826C (en) 1999-01-05
JP3527721B2 (en) 2004-05-17
ES2246491T3 (en) 2006-02-16
EP0639070A1 (en) 1995-02-22
DE69333850D1 (en) 2005-09-08
DE69333850T2 (en) 2006-01-12
AU4233693A (en) 1993-11-29
DE69333850T3 (en) 2011-03-17

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Legal Events

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EEER Examination request