CA2128567A1 - Thrombectomy method and apparatus - Google Patents

Thrombectomy method and apparatus

Info

Publication number
CA2128567A1
CA2128567A1 CA002128567A CA2128567A CA2128567A1 CA 2128567 A1 CA2128567 A1 CA 2128567A1 CA 002128567 A CA002128567 A CA 002128567A CA 2128567 A CA2128567 A CA 2128567A CA 2128567 A1 CA2128567 A1 CA 2128567A1
Authority
CA
Canada
Prior art keywords
brush
soft
thrombus
drive shaft
lumen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002128567A
Other languages
French (fr)
Other versions
CA2128567C (en
Inventor
Andrew H. Cragg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Covidien LP
Original Assignee
Andrew H. Cragg
Micro Therapeutics, Inc.
Ev3 Inc.
Ev3 Llc
Tyco Healthcare Gr0Up Lp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Andrew H. Cragg, Micro Therapeutics, Inc., Ev3 Inc., Ev3 Llc, Tyco Healthcare Gr0Up Lp filed Critical Andrew H. Cragg
Publication of CA2128567A1 publication Critical patent/CA2128567A1/en
Application granted granted Critical
Publication of CA2128567C publication Critical patent/CA2128567C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0043—Catheters; Hollow probes characterised by structural features
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B2017/22082—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for after introduction of a substance
    • A61B2017/22084—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for after introduction of a substance stone- or thrombus-dissolving
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/32—Surgical cutting instruments
    • A61B2017/320004—Surgical cutting instruments abrasive
    • A61B2017/320012—Brushes

Abstract

A thrombectomy system for dissolving a soft fibrinous obstruction, such as a recently formed thrombus, within a patient's vascular system, either in a patent vein or artery or in a prosthetic implant, employing a soft rotating brush for separating and mixing the fibrin of the thrombus while a dissolving agent, e.g. streptokinase or urokinase, is introduced and mixed in and applied to the separated fibrin.
The system includes an introducer catheter adapted to be introduced and advanced through a patient's blood vessels until the distal end is positioned adjacent the soft fibrinous thrombus, the brush attached to an elongated, flexible, rotatable drive shaft having a drive motor attached at its proximal end, the drive shaft and brush passed through the introducer lumen to place the brush in contact with the soft thrombus. The brush has soft, flexible bristles extending outward from the drive shaft distal end, the bristles being sufficiently resilient and dimensioned for enabling compression and passage of the brush out of and back into the distal end of the introducer lumen and effective to mix into then fibrin of the soft thrombus, yet not damage the vessel wall. The dissolving agent is introduced during rotation of the brush either through the introducer catheter lumen or a drive shaft lumen and out exit ports at the distal ends thereof in the region of rotation of the brush for dissolving the soft thrombus as it is contacted by the bristles. Optionally, a balloon catheter or a mesh basket may be coaxially introduced through the drive shaft lumen and placed downstream to restrain fragments and to allow the dissolving agent to complete the dissolution thereof.
CA002128567A 1993-07-22 1994-07-21 Thrombectomy method and apparatus Expired - Fee Related CA2128567C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/095,867 US5370653A (en) 1993-07-22 1993-07-22 Thrombectomy method and apparatus
US08/095,867 1993-07-22

Publications (2)

Publication Number Publication Date
CA2128567A1 true CA2128567A1 (en) 1995-01-23
CA2128567C CA2128567C (en) 2001-12-04

Family

ID=22253947

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002128567A Expired - Fee Related CA2128567C (en) 1993-07-22 1994-07-21 Thrombectomy method and apparatus

Country Status (5)

Country Link
US (1) US5370653A (en)
EP (1) EP0635242B1 (en)
JP (1) JPH07171156A (en)
CA (1) CA2128567C (en)
DE (1) DE69419075T2 (en)

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JPH07171156A (en) 1995-07-11
EP0635242B1 (en) 1999-06-16
DE69419075D1 (en) 1999-07-22
EP0635242A1 (en) 1995-01-25
CA2128567C (en) 2001-12-04
DE69419075T2 (en) 1999-12-23
US5370653A (en) 1994-12-06

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