CA2003009A1 - Method and composition for reducing postsurgical adhesions - Google Patents

Method and composition for reducing postsurgical adhesions

Info

Publication number
CA2003009A1
CA2003009A1 CA2003009A CA2003009A CA2003009A1 CA 2003009 A1 CA2003009 A1 CA 2003009A1 CA 2003009 A CA2003009 A CA 2003009A CA 2003009 A CA2003009 A CA 2003009A CA 2003009 A1 CA2003009 A1 CA 2003009A1
Authority
CA
Canada
Prior art keywords
composition
postsurgical adhesions
peritoneal
reducing
pleural cavity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2003009A
Other languages
French (fr)
Other versions
CA2003009C (en
Inventor
Raymond L. Henry
Richard E. Leach
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MDV Technologies Inc
Original Assignee
Raymond L. Henry
Richard E. Leach
Mediventures Inc.
Mdv Technologies, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Raymond L. Henry, Richard E. Leach, Mediventures Inc., Mdv Technologies, Inc. filed Critical Raymond L. Henry
Publication of CA2003009A1 publication Critical patent/CA2003009A1/en
Application granted granted Critical
Publication of CA2003009C publication Critical patent/CA2003009C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/745—Polymers of hydrocarbons
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A61K31/77—Polymers containing oxygen of oxiranes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/06—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

A process and compositions for reducing post-surgical adhesion formation/reformation in mammals following surgical injury to the peritoneal or pleural cavity or organs situated therein. Both aqueous and non-aqueous compositions comprising a polyoxyalkylene block copolymer are applied to injured areas of the peritoneal or pleural cavity or organs situated therein subsequent to surgical injury.
CA002003009A 1988-11-16 1989-11-15 Method and composition for reducing postsurgical adhesions Expired - Fee Related CA2003009C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US272,199 1988-11-16
US07/272,199 US4911926A (en) 1988-11-16 1988-11-16 Method and composition for reducing postsurgical adhesions

Publications (2)

Publication Number Publication Date
CA2003009A1 true CA2003009A1 (en) 1990-05-16
CA2003009C CA2003009C (en) 2000-05-02

Family

ID=23038822

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002003009A Expired - Fee Related CA2003009C (en) 1988-11-16 1989-11-15 Method and composition for reducing postsurgical adhesions

Country Status (9)

Country Link
US (2) US4911926A (en)
EP (1) EP0369764B1 (en)
JP (1) JPH0647549B2 (en)
KR (1) KR900007425A (en)
AU (1) AU616065B2 (en)
CA (1) CA2003009C (en)
DE (1) DE68916512T2 (en)
DK (1) DK173130B1 (en)
PH (1) PH26319A (en)

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Also Published As

Publication number Publication date
DK571389D0 (en) 1989-11-15
US4911926A (en) 1990-03-27
DK571389A (en) 1990-05-17
EP0369764A2 (en) 1990-05-23
CA2003009C (en) 2000-05-02
PH26319A (en) 1992-04-29
EP0369764A3 (en) 1991-08-28
KR900007425A (en) 1990-06-01
JPH02200638A (en) 1990-08-08
AU4441689A (en) 1990-05-24
AU616065B2 (en) 1991-10-17
JPH0647549B2 (en) 1994-06-22
US5366735A (en) 1994-11-22
DE68916512D1 (en) 1994-08-04
EP0369764B1 (en) 1994-06-29
DE68916512T2 (en) 1994-10-27
DK173130B1 (en) 2000-01-31

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