CA1291254C - Multiwavelength laser source - Google Patents

Multiwavelength laser source

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Publication number
CA1291254C
CA1291254C CA000578516A CA578516A CA1291254C CA 1291254 C CA1291254 C CA 1291254C CA 000578516 A CA000578516 A CA 000578516A CA 578516 A CA578516 A CA 578516A CA 1291254 C CA1291254 C CA 1291254C
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CA
Canada
Prior art keywords
laser source
cited
laser
pulses
light
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA000578516A
Other languages
French (fr)
Inventor
Josef F. Bille
Stuart I. Brown
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Intelligent Surgical Lasers Corp
Original Assignee
Intelligent Surgical Lasers Corp
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Filing date
Publication date
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Application granted granted Critical
Publication of CA1291254C publication Critical patent/CA1291254C/en
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Classifications

    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01SDEVICES USING THE PROCESS OF LIGHT AMPLIFICATION BY STIMULATED EMISSION OF RADIATION [LASER] TO AMPLIFY OR GENERATE LIGHT; DEVICES USING STIMULATED EMISSION OF ELECTROMAGNETIC RADIATION IN WAVE RANGES OTHER THAN OPTICAL
    • H01S3/00Lasers, i.e. devices using stimulated emission of electromagnetic radiation in the infrared, visible or ultraviolet wave range
    • H01S3/005Optical devices external to the laser cavity, specially adapted for lasers, e.g. for homogenisation of the beam or for manipulating laser pulses, e.g. pulse shaping
    • H01S3/0057Temporal shaping, e.g. pulse compression, frequency chirping
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007Methods or devices for eye surgery
    • A61F9/008Methods or devices for eye surgery using laser
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007Methods or devices for eye surgery
    • A61F9/008Methods or devices for eye surgery using laser
    • A61F9/00802Methods or devices for eye surgery using laser for photoablation
    • A61F9/00804Refractive treatments
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B23MACHINE TOOLS; METAL-WORKING NOT OTHERWISE PROVIDED FOR
    • B23KSOLDERING OR UNSOLDERING; WELDING; CLADDING OR PLATING BY SOLDERING OR WELDING; CUTTING BY APPLYING HEAT LOCALLY, e.g. FLAME CUTTING; WORKING BY LASER BEAM
    • B23K26/00Working by laser beam, e.g. welding, cutting or boring
    • B23K26/02Positioning or observing the workpiece, e.g. with respect to the point of impact; Aligning, aiming or focusing the laser beam
    • B23K26/06Shaping the laser beam, e.g. by masks or multi-focusing
    • B23K26/062Shaping the laser beam, e.g. by masks or multi-focusing by direct control of the laser beam
    • B23K26/0622Shaping the laser beam, e.g. by masks or multi-focusing by direct control of the laser beam by shaping pulses
    • B23K26/0624Shaping the laser beam, e.g. by masks or multi-focusing by direct control of the laser beam by shaping pulses using ultrashort pulses, i.e. pulses of 1ns or less
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01SDEVICES USING THE PROCESS OF LIGHT AMPLIFICATION BY STIMULATED EMISSION OF RADIATION [LASER] TO AMPLIFY OR GENERATE LIGHT; DEVICES USING STIMULATED EMISSION OF ELECTROMAGNETIC RADIATION IN WAVE RANGES OTHER THAN OPTICAL
    • H01S3/00Lasers, i.e. devices using stimulated emission of electromagnetic radiation in the infrared, visible or ultraviolet wave range
    • H01S3/23Arrangements of two or more lasers not provided for in groups H01S3/02 - H01S3/22, e.g. tandem arrangements of separate active media
    • H01S3/2308Amplifier arrangements, e.g. MOPA
    • H01S3/2325Multi-pass amplifiers, e.g. regenerative amplifiers
    • H01S3/235Regenerative amplifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007Methods or devices for eye surgery
    • A61F9/008Methods or devices for eye surgery using laser
    • A61F2009/00861Methods or devices for eye surgery using laser adapted for treatment at a particular location
    • A61F2009/00872Cornea

Abstract

ABSTRACT
A multiwavelength laser source for providing a plurality of pulsed laser beams comprises a plurality of laser diodes optically connected with an oscillator to establish a beam of pulses of monochromatic light. A dispersion line for spreading wavelengths in each pulse optically connects the oscillator to a regenerative amplifier. An electro-optical crystal in the regenerative amplifier establishes the repetition rate of pulses in the laser beam and a pulse compressor is optically connected to the regenerative amplifier to establish the duration of each pulse. The laser source may also include a frequency doubler which is optically connected to the output of the pulse compressor to split the laser beam into components having different wavelengths.

Description

-~

1 BA~KGRO~ND OF THE INVE~TLO~
2 This invention relates generally to m~ltiwavelen~tl~ laser 3 sources. More oarticularly, this invention relates to a lasec source which establishes a multiwavelength beam of laser ou]ses , in which the duration of each pulse is extremely snort and in 6 which the repetition rate for pulses in a given unit of time is 7 very high. This invention is particularly, but not 8 exclusively, useful for ophthalmic surgery.

DISCUSSION OF THE PRIOR ART
-Lasers have been used for various purposes with profound 12 results for many years. Although the theories of this 13 technology are complicated and highly sophisticated, a general 14 understanding of several basic notions underlying the technical complications is sufficient to appreciate the contributions 16 made by the present invention.
17 As is well known to the skilled artisan, laser beams are 1~ intense light-frequency radiations of highly collimated 19 coherent monochromatic light. Further, it is known that laser beams can be generated by the proper excitation of selected active media, including gases or crystals, in a process 22 commonly referred to as "pumping. n Just how the resultant 23 radiated light in a laser beam is constituted is the concern of 24 the present invention.
The most important parameters for understanding the basic 26 uses of laser technology are the wavelength of the radiations, --~

1 the duration of these radiations and their intensity. As ~
2 be readily appreciated, variations in these parameters are made 3 to optimize the efficacy of the laser beam for the particular ~ purpose it is being employed. When used for ophthalmic r~ surgery, several specific considerations become important.
6 Primarily, the concern in ophthalmic surgery, like that in 7 other surgical applications, centers on factors which enhance 8 the ability to perform the required surgical operation while 9 minimizing trauma to the tissue~ A thorough discussion of this ~o matter is set forth in an article entitled "Laser Interactions 11 with the Cornea" by Joel M. Krauss et al. and published in 12 Survey of Ophthalmology, Volume 31, Number l, July-August 13 1986. Not surprisingly, the Krauss article and other 14 references believe the constituency of the laser beam significantly determines its efficacy for ophthalmic surgery.
16 With this in mind, a basic understanding of laser beams is ` 17 helpful.
1~ Many articles have been written on the importance of a laser beam's wavelength. As is well known, the interaction between a laser beam and the human tissue on which it is incident is wavelength dependent. This is so because different 22 tissues have different absorption characteristics.
23 Consequently, laser sources must be carefully selected 24 depending on the purpose for which they are to be used. Since each active medium has its characteristic wavelength, any 26 variation in this parameter is essentially a matter of :.

l choice. This is not so with the other important variables 2 dealing with laser beam intensity and duration.
:3 Insofar as duration is concerned, lase~ beams can be 4 generally cateyorized as either continuous beams or pulsed S beams. It happens that pulsed laser beams are more effective 6 than are the con~inuous laser beams for most medical 7 procedures. With the continuous beam, the duration of the 8 laser beam lasts as long as the beam is turned on. On the 9 other hand, the duration of a pulsed beam is more properly considered as referring to the sum of the durations of individual pulses. Presently, pulses in the picosecond range 12 (1 ps = 1 picosecond = 10 seconds) are attainable but not 13 practically useable for ophthalmic surgery. Instead, pulses in 14 the nanosecond range are typically used (1 ns = 1 nanosecond =
_g seconds).
16 Typically, in surgical procedures when a pulsed beam is 17 used, groups of pulses are employed in bursts. Unlike such 1~ structure for a laser beam, in the contemplation of the present invention, a pulsed laser beam is established which is really quasi-continuous in nature. Thus, the laser beam established by the laser source of the present invention establishes a , continuous train of pulses having equal energy and time duration and a very high repetition rate.
~ As stated above, wavelength, duration and intensity are S all important parameters for describing the characteristics of !6 a laser beam. Not unexpectedly, these parameters are ,~. .;. :
`:

`~"\ ~ s~

1 interrelated. Speci~ically, these variables are related to 2 each other according ~o the expressions:

P = t , and nhc ~. E = ~ ; where 6 P is in~ensity or cutting power, E is energy, t is pulse _ duration, h is Planck's constant, c is the speed of light, ~ is 8 wavelength and n is the number of photons per pulse.
9 It will be seen from the above expressions that energy (E) is inversely proportional to the wavelength of the light (~).
ll Also, from the above expression for intensity (P), it will be 12 seen that if the duration (t) of each pulse can be effectively 13 reduced, the intensity or cutting power of the laser beam can 14 be maintained even though pu]ses of lower energy having longer wavelengths are used. It happens that several procedures of 16 ophthalmic surgery are effective only when longer wavelength 17 laser pulses are employed. Consequently, the ability to 18 control duration (t) becomes extremely important.
19 Presently used laser surgical procedures recognize that it is the energy of a laser beam, i.e. the number of photons in 21 the beam or pulse, which determines the effect the beam has on 22 tissue. This effect can be generally described as either 23 thermal, or electromechanical or a combination thereof. As is 24 well known, although the effect should be highly localized to achieve an efficacious result, the relatively high energy .,, .. - ; . .

l levels of presently used laser beams invariably cause 2 unnecessary damage ~o peripheral tissue.
3 rrhe present invention recogni~es that both the cutting of 4 tissue and changes in the elastic properties of tissue can be S achieved with an electric field effect which obviates the 6 adverse peripheral consequences of the thermal and 7 electromechanical effects mentioned above. While a complete 8 disclosure of the electric field effect is beyond the scope of 9 this application, it is deemed important to note that, unlike the thermal and electromechanical effects, this effect does not depend on the energy in a laser beam. Instead, lt depends on 12 the beam's intensity, i.e. the number of photons striking the 13 target area in a given unit of time. Thus, whenever the 14 electric field effect is to be used to alter tissue structure, the goal is to maintain a beam intensity which is sufficient to 16 accomplish this end while reducing the beam's energy level to a 17 point where unwanted thermal and electromechanical effects are 18 confined to a highly localized area. Fcom the expression 19 P = - , however, it will be understood that energy and intensity are proportional. Therefore, intensity can be 21 generally maintained whenever energy is reduced only if pulse 22 duration (t) is also reduced.
23 In accordance with the present invention, the pulse 24 durations of a laser beam are greatly reduced from those presently achieved in other laser beams by today's state--of-26 the-art technology. The well known excimer laser, for . .

~ ~o_~d f~ 5~

l instance, typically produces pulses of lO nanosecon~
2 duration. The present invention, on the other hand, envisions :, pulses of one oe only a few picosecond duration. This is a 4 reduction in pulse duration by a factor of approximately ten thousand. Also, in order to reduce the adverse effects to 6 peripheral tissue caused by thermal or electromechanical , alterations, the present invention envisions energy levels in 8 each pulse which are a factor of one thousand less than the 9 levels attained in presently used laser beams. The result is a beam which has an intensity level that is approximately ten times higher than the intensity levels attained in commonly 12 used laser beams at this time. Accordingly, the electric field 13 effect is enhanced and the thermal and electromechanical 14 effects are minimized.
Another factor which figures into the efficacy of the 16 present invention is focal area. Again reference is made to 17 the popular excimer laser which affects areas approximately one 18 hundred microns in diameter. In stark contrast to such focal 19 areas, the present invention envisions affecting areas approximately one micron in diameter. Additionally, it will be 21 appreciated that, although short duration pulses are used, the 22 total power available to cut the tissue will be the sum of the 23 cutting powers for each pulse. Therefore, it follows that 24 repetition rate is also a major consideration in developing an effective ophthalmic laser. Accordingly, rather than hit the 26 target are with a burst oi energy over a large target area, as ,,, ' , .

, l has been the practice, it is the purpose of the present 2 invention to affect many small target areas with sufficient 3 intensity to efEectively change the photoelastic properties of 4 the tissue. In this way, the present invention accomplishes ~s the same desirable effect as the high energy beam without 6 suffering the adverse effects on peripheral tissue. Briefly, 7 the present invention is intended to produce a quasi-continuous 8 beam of high-intensity low-energy pulses which can be aimed at 9 different selected target areas at a very high repetition rate.
10In light of the above, recall that the wavelength of the 11light in a lasee beam is dependent on the active medium used 12and that different wavelengths have different effects on human 13tissue. Accordingly, it is important to select an active 14medium which can be based to produce light having the desired 15wavelength. Importantly, however, the combined effect of these 16variables will determine whether the tissue is affected 7thermally or electromechanically to achieve the desired 8.result. Thus, the ability to control pulse duration and ~9intensity is crucial.
~0The present invention recognizes that the most effective 21and efficacious way in which to cut eye tissue is by a 22procedure known in the art as photoablation. With this 23procedure, pulses preferably have very short durations, e.g.
2~1-40 picoseconds, with high repetition rates, e.g. in a range 25of ten thousand (lO,000) to one million (l,000,000) pulses per 26second. Further, the present invention recognizes that the --l above-mentioned electric field effect can be used either to 2 mechanically sever the bonds ~e~ween ce]l ti.ssue to create an incision or to alter the elas~ic properties of the cells and change their interactive bonds with other cells. The 5 particular result obtained depends on the selection of fi wavelength. With this in mind, the present invention ~ recognizes that, for specific applications in ophthalmic 8 surgery, exteenal ablation (mechanical severance) can be (3 accomplished on corneal tissue with a laser beam having a wavelength of 2.94 microns and that internal ablation (elastic l alteration) can be accomplished on corneal tissue with 12 wavelengths of l.06 and 0.532 microns. I'he intention of the 13 present invention is to incorporate a crystal capable of 14 producing a multiwavelength beam useful for electric field effect on corneal tissue having all these wavelengths. This, 16 however, cannot be construed as a limitation for the present 17 invention. Indeed, the present invention will be useful in 18 angioplasty procedures and neurosurgical procedures depending 19 upon the active medium chosen. Accordingly, it is to be appreciated that any active medium can be used with the present 21 invention depending only on the procedural requirements and the 22 consequent efficacious laser wavelengths.
23 Besides applications in ophthalmic surgery, the new laser 24 source has many other uses in medical surgery. Modern optical systems and fiber-optic catheters can be configured to deliver 26 laser light to virtually anywhere in the body. For example, in , laser angiosurgery, laser light can be passed through an optical fiber to clear plaque ~rom blocked arteries.
itially, CW-Argon ion and Nd:YAG lasers were used in experimental trials for angiosurgery. Recently, the pulsed ultraviolet radiation of excimer lasers has been studied which _ allows for the destruction of calcified plaques. The accompanying problem of blood vessel wall perforation, however, has not been satisfactorily solved until now~ The laser source (~ described in this invention applied through an imaging optical fiber bundle will allow for a substantially improved control of 11 the photoablation process.
1, Similarly, in laser lithotripsy, which is proving to be an 13 effective substitute for acoustic techniques in many cases, 14 kidney or gall bladder stones can be destroyed with greatly ls enhanced precision.
16 In neurosurgery, a new laser source according to the present invention will spare more of the surrounding delicate tissue than possible until now. In ear surgery, the finely ~ focused laser beam can be used to selectively vaporize material O to free the stapes, after which they can be gently lifted out 1 and replaced with artificial parts. The procedure reduces 2 bleeding and greatly reduces damage to the delicate inner 3 ear. Recovery will be more comfortable and rapid.
24 Among many potential industrial applications, the new laser source provides a fast and precise tool for cleaning and _g_ .

1 etching of ~LSL microstructures. Many other applications in , micromachining are feasible.
3 In light o~ the above, it is an object o~ the present invention to provide a pulsed laser light source which provides very short duration pulses at extremely high repetition ~ rates. It is another object o the present invention to 7 provide a laser source in which both the pulse duration and the repetition rate can be varied. Yet another object of the 9 present invention is to provide a laser source which is compatible with various active media to obtain useful wavelengths which are efficacious for the desired procedure.
12 Still another object of the present invention is to provide a 13 multiwavelength laser system which is relatively easy to 14 manufacture and which is cost effective.
~

17 A preferred embodiment of the novel multiwavelength laser 18 source, according to the present invention, includes a 19 plurality of laser diodes which provide input to a laser oscillator. The oscillator includes an active medium, such as 21 a crystal, which is pumped by light from the laser diodes to 22 create a laser beam having predetermined wavelengths. In 23 accordance with the present invention a YSGG:Cr:Nd:Er crystal 24 is preferably ~sed to produce a laser beam having desired multiwavelengths. An acousto-optic mode locker is incorporated . .

-~ Z~

into the oscillator to divide light radiating along the optical , axis of the oscillator into pulses.
3 A dispersion line is optically connected to the output of the oscillator for the purpose of spreading wavelengths within the pulses of the laser beam. Preferably, this dispersion line . comprises a monomode optical fiber which is approximately 20 meters in length. The pulses emanating from the dispersion ~ line are optically directed toward a regenerative amplifier 9 where pulses in the laser beam are a~plified. Subsequently, an electro-optical crystal within the regenerative amplifier is Il selectively activated to vary the plane of polarization of the 12 pulses. With a first change in the plane of polarization by 13 the electro-optical crystal, the pulses are captured in the 14 amplifier and are amplified in the regenerative amplifier by their interaction with a laser pumping chamber. With 16 sequential change in the plane of polarization by the electro-ll optical crystal, amplified pulses are diverted from the 1~ regenerative amplifier and directed toward a pulse 19 compressor.
The pulse compressor comprises a grating optically 21 connected with a corner cube that is moveable relative to the 22 grating. According to the distance of the corner cube from the 23 grating, the duration of each pulse can be established. A
24 frequency doubler may also be incorporated in cooperative association with the pulse compressor to provide a pulsed laser :

``-beam having hal~ the wavelength of the pulsed laser beam ~, generated at the oscillator.
:3 The novel features o~ this invention, as well as the invention itself, both as to its structure and its operation, . will be bes~ understood from the accompanying drawings, taken 6 in conjunction with the accompanying description, in which _ similar reference characters refer to similar parts, and in 8 which:

BRIEF DESCRIPTION OF THE DRAWINGS
Figure l is a block diagram showing the operative 12 connection of components of the laser source according to the 13 present invention;
14 Figure 2 is a schematic diagram of the oscillator of the present invention;
16 Figure 3 is a schematic diagram of the line dispersion component of the present invention;
18 Figure 4 is a schematic diagram of the regenerative 19 amplifier of the present invention; and Figure 5 is a schematic diagram of the pulse compressor of 21 the present invention.

23 DESCRIPTION OF T~E PREFERRED EMBODIMENT
24 Referring initially to Figure l, it will be seen that the ?5 multiwavelength laser source in accordance with the present '6 invention is generally designated lO and comprises several ,:

-~ 5-~

I components. Specifically, ml~ltiwavelength laser source 10 , includes an array 12 of laser diodes which provide the optical 3 input to oscillator 14 necessary to excite the active medium.
The result is a mode locked pulsed laser beam 16 as an output from oscillator 14. Pulsed laser beam 16 is directed by ~, turning mirror 18 into a dispersion line 20 where the _ wavelengths of light in the pulses of beam 16 are spread. As 8 beam 16 emerges from dispersion line 20 it is directed by 9 turning mirror 22 toward regenerative amplifier 24 where the lo individual pulses in beam 16 are amplified. Additionally, in a ll manner ~o be subsequently discussed, the repetition rate of 12 pulses in beam 16 for any given period of time is established 13 within regenerative amplifier 24. Upon being diverted from 14 regenerative amplifier 24, laser beam 16 is directed by turning mirror 26 toward pulse compressor 28 where the duration of each 16 pulse in laser beam 16 is established. As shown in Figure 1, 17 pulse compressor 28 has means to selectively create pulsed laser beams 16a and 16b having different wavelengths. A
greater appreciation of the laser source 10 of the present invention will be obtained by reference to each component 21 individually.
22 Referring to Figure 2, it will be seen that array 12 of 23 oscillator 14 includes a laser diode 30 which has its light ~4 directed through collimator lens 32 into beam splitter 34.
Likewise, a laser diode 36 is incorporated wlth its light beam i 26 directed t ro~gh collimat~ s 38 into beam splitter 34. At ` ~ ~
.

`' '`.

I beam splitter 34, li~ht from laser diodes 30 and 36 are ~2 combined and directed through cylindrical lens 40. Figure 2 :3 also shows that additional structure is provided with laser 1 diode 42 directing its light through colli~ator lens 44 and . into beam splitter 46 while laser diode 48 directs its light 6 through collimator lens 50 and into beam splitter 46. At beam 7 splitter 46, the light from laser diodes 42 and 48 are combined 8 and passed through cylindrical lens 52. As shown in Figure 2, the light passing through cylindrical lens 40 and the light passing through cylindrical lens 52 are both incident on ll crystal 54. The skilled artisan will recognize this 12 combinatian of laser diodes, beam splitters and cylindrical 1~ lenses as a pumping chamber. Preferably laser diodes 30, 36, 14 42 and 48 are of the type SLD 2460.
In accordance with the present invention, the active medium is a crystal 54 whicn is preferably a YSGG:Cr:Nd:Er `7 cyrstal. It is to be understood, however, that the particular YSGG:Cr:Nd:Er crystal 54 is only exemplary. Indeed, any active medlum may be used within the spirit of the present invention to provide a laser beam which will have the desired characteristics. It is known that upon being properly pumped '2 by peripheral laser sources such as laser diodes 30, 36, 42 and 23 48 that a YSGG:Cr:Nd:Er crystal 54 will generate laser beams 24 having wavelengths of l.06 microns and 2.94 microns. For purposes to be subsequently discussed, a portion of the l.06 26 micron wavelength laser beam can be subsequently diverted .` , ` ` ' '' ' , ' , .

-~

through a ~requency doubler to establish a laser beam having a ~) wavelength o~ 0.532 microns. Thus, in accordance wi~h the 3 present invention, most active media, such as crystal 54 described here, will provide a laser source lO which is capable o~ generating laser beams of three different ~avelengths. For (, reasons previously stated, this adds versatility to the system _ and allows its use in a wider variety of procedures.
~ Still referring to Figure 2, it can be seen that portions 9 of the laser light generated by pumping crystal 54 will radiate along optical axis 56. Further, it will be appreciated by the ll skilled artisan that laser light radiating along optical axis 12 56 will reciprocate along axis 56 between a curved lO0~ mirror 13 58 and a flat 98% mirroL 64, through an aperture 60 and through 14 an acousto-optic mode locker 62. The operation of acousto~
optic mode locker 62 in combination with crystal 54 and 16 aperture 60, as well as the reflection of laser light along 17 optical axis 56 between mirrors 58 and 64 is well known. The 18 result is an output ~rom oscillator 14 which is best 19 characteri~ed as a pulsed laser beam 16.
~eferring now to Figure 3, it is seen that the optical 21 connection between oscillator 14 and dispersion line 20 is 22 accomplished by turning mircor 18. Dispersion line 20 23 comprises an objective lens 66 which focuses beam 16 onto an 24 optical fiber 68. Preferably, optical ~iber 68 is a monomode optical fiber approximately 20 meters in length of a type well 26 known in the art. In accordance with the present invention, , -15 ' .. ,. . ',. . .
~ .
,:

--l pulses in beam 16 whicll are emitted frorn oscillator 14 pass ? through optical fiber 68 where, by virtue of the differences in :~ the path length followed by pu],ses in beam 16 as they pass .~ through optical fiber 68, the wavelengths within each pulse o .; beam 16 are spread. Once wavelengths in beam 16 have been 6 spread in their passage through optical fiber 68, objective i lens 70 refocuses the pulses of beam 16 as they emerge from 8 optical fiber 68. As shown in Figure 3, pulsed laser beam 16 9 is then directed from dispersion line 20 into regenerative amplifier 24 by the action of turning mirror 22.
In Figure 4 it will be seen that pulsed laser beam 16, 1'2 after being reflected by turning mirror 22, is incident upon an l3 uncoated glass beam splitter 72. The uncoated glass beam l4 splitter 72 diverts a portion of laser beam 16 toward lS polarizing beam splitter 74 and directs the remainder of pulsed 16 laser beam 16 toward photodiode trigger 76. That portion of .7 pulsed laser beam 16 which is diverted by uncoated glass beam l8 splitter 72 toward polarizing beam splitter 74 is polarized by l9 beam splitter 74 and directed along optical path 78. In '0 sequence, pulses of laser beam 16 pass through quarterwave l plate 80 and electro-optical crystal 82 and are incident upon a :2 flat 100~ mirror 84 where they are reflected back through !3 electro-optical crystal 82 and quarterwave plat~e 80. It is to 24 be understood that quarterwave plate 80 is of any type well ?5 known in the pertinent art and that electro-optical crystal 82 6 is of the type generally known as a Pockels' cell.

.~

'`' ' :

. .

-After being reflected by flat 100~ mirror 84 through ~,quarterwave plate 80 on optical path 78, the pulse has passed 3through quarterwave plate 80 twice. This causes the plane of polarization of pulses in ]aser beam 16 to be rotated a total ~,of 90 degrees. This rotation allows the pulses to pass through 6polarizing beam splitter 74 and continue along optical path 78 7to be successively incident upon crystal 86, pass through 8aperture 88 and be reflected back through aperture 88 and 9crystal 86 by curved 100% mirror 90. It will be understood lOthat during this initial passage of beam 16 through ~1regenerative amplifier 24, crystal 82 is not activated. During 12subsequent passages, however, pulses in laser beam 16 can be 13confined within regenerative amplifier 24 for reciprocal l4reflection along optical path 78 depending upon further 15rotations in polarization imparted to the pulses of laser beam 1616 as they pass through electro-optical crystal 82. If 17electro-optical crystal 82 is activated by electronic switch 92 18to rotate each pulse an additional 90 degrees during its two l9passes through electro-optical crystal 82, both quarterwave 20plate 80 and crystal 82 will combine their effects to rotate ~1the plane of polarization of each pulse 180 degrees. Thus, 22each time a pulse is incident on polarizing beam splitter 74, 23it will pass therethrough and be effectively captured in 24reflectlons along optical path 78. Subsequently, in accordance 25with the predetermined desires of the operator, electronic 26switch 92 can activate electro-optical crystal 82 to rotate the , ," ~ `" ' ;~..- - :
:

plane oE polarization of each pulse 18~ degrees during two ~ excursions of the pulse ~hrough electro-optical crystal 82.
:~ This rotation by electro-optical cyrstal 82, in its colnbined 4 effect with the rotation caused by quarterwave plate 80 brings .. each pulse of laser beam 16 into a polarization alignment for (, reflection of the pulse out of optical path 78 by the 7 polarizing beam splitter 74.
~In accordance with the above described operation, pulses 9 in laser beam 16 are accepted by regenerative amplifier 24 for reflection along optical path 78. Then, in accordance with the ll activation of electro-optical crystal 82 to rotate the plane of 12 polarization 90 degrees during the two passages of the pulse 13 through electro-optical crystal 82, the puIses are retained 14 within regenerative amplifier 24 for reflection back and forth 15along optical path 78 between flat lO0~ mirror 84 and curved 16 lO0~ mirror 90. Subsequent activation of electro-optical crystal 82 into a state which imparts a 180 degree rotation to 1~ the polarization of light in the pulses will cause reflection 19 of the amplified pulse out of optical path 78 by polarizing beam splitter 74.
21Figure 4 also shows that pulsed laser beam 16, as it 22 passes along optical path 78, is influenaed by a pumping 23 chamber similar to the pumping chamber used in cooperation with 24 oscillator 14.~ Within this pumping chamber, laser diode 94 directs its light through collimating lens 96 and laser diode 26 98 directs its light through collimating lens lO0.. Light from .

,.~

3~ /.d 9~
1 laser diodes 94 and g8 aee combined at beam splitter 102 and 2 directed through cylindrical lens 104. Likewise, laser diode :~ 106 in cooperation with a collimating lens 108 and laser diode 4 110 in cooperation with collimating lens 11~ pass collimated .5 light through beam splitter 114 and direct it through 6 cylindrical lens 116. Light from both cylindrical lens 104 and 7 116 are then directed to be incident upon crystal 86 in a 8 manner similar to the discussion above relative to crystal 9 54. Preferably, crystal 86, like crystal 54, is a YSGG:Cr:Nd:Er.
Figure 4 also schematically shows the location of 1'2 photodiode trigger 76 and electronic switch 92 relative to the l3 electro-optical crystal 82. It is to be understood that the l4 portion of each pulse in laser beam 16 which passes through uncoated glass beam splitter 72 is incident upon photodiode trigger 76 which can be timed to sequentially activate 7 electronic switch 92. Electronic switch 92, in turn, activates 8 electro-o~tical crystal 82 into the polarizing regime necessary 9 to capture a pulse of laser beam 16 on optical path 78 and keep 0 it there during the time required for amplification of the ~l pulses in beam 16. Crystal 82 is also activated by electrical 22 switch 92 to the level which, in accordance with the previous 23 disclosure, polarizes pulses for reflection by beam splitter 74 24 out of optical path 78. Figure 4 also shows that when pulses of laser beam 16 are reIected out of optical path 78, they 26 pass through uncoated glas~ beam splitter 72 and are incident ' _19_ :.
. .
, .. . . . .
.

-, on turning mirror 26 for further radiation toward pulse 2 compressor 28.
:~ Figure S shows that, after ref],ection frorn turning mirror 26, laser beam 16 is incident upon grating 118. After its s interaction with grating 118, laser beam 16 is further 6 reflected toward corner cube 120 where it is reflected along an 7 offset path back to grating 118. From grating 118, laser beam 8 16 is incident on 50% mirror 122 which reflects half of beam 16 9 as a separate laser beam 16a having a predetermined wavelength. The 50% of laser beam 16 which passes through 50%
Il mirror 122 is incident on 100% mirror 124 and directed toward a frequency doubler 130.
13 It will be appreciated by the skilled artisan that the 14 duration of each pulse in beam 16 can be controlled by selecting the distance at which corner cube 120 is placed from l6 grating 118. For this purpose, a rail 126 is provided in operative association with corner cube 120 for movement of l8 corner cube 120~in the dlrections indicated by arrow 128. It 19 will 'be further appreciated by the skilled artisan that movement of corner cube 120 in the directions indicated by 21 arrow 128 will cause determinable changes in the duration of 22 each pulse in laser beam 16. More specifically, a position 23 change of 45 centimeters by corner cube 120 will cause a 24 duration, change in each pulse from 40 picoseconds to picosecond.

: -20-..
. ,; :
: :i :, .
:

.
. :.. . . :
,: ' ' , .

_~ ~si ~

l After reflection from 50~ mirror 122, laser beam 16a is 2 placed into operation in accordance with the desires of the :3 operator. Likewise, that portion o laser beam 16 which passes through 50% mirror 122, for incidence upon 100~ mirror 124, is reflected by lO0~ mirror 124 and into a frequency doubler 6 130. Consequently, the wavelength of light in each pulse of 7 laser beam 16 emerging from frequency doubler 130 is half the ~ wavelength of the light which is directed toward frequency 9 doubler 130. The result is that laser beam 16b, having half the wavelength of laser beam 16a, is provided for use in accordance with the desires of the operator. Specifically, 12 each pulse generated by the laser source 10 will contain a 13 visible component of approximately 1.06 micron wavelength which 1.~ can be passed through frequency doubler 130 to establish another component having a wavelength of approximately 0.532 16 microns. These are components of visible light which are 17 effective for internal ablation procedures. Also, laser source l~ 20 simultaneously produces a component of light having a 19 wavelength of approximately 2.94 microns. This is an infrared component which is useful for external ablation. It follows 21 that once these components are generated, means for selectively 22 focusing the desired component is employed in cooperation with ` 23 laser source 10.
2~ While the particular multiwavelength laser source as herein shown and disclosed in detail is fully capable Gf 26 obtaining the objects and providing the advantages herein .
.. " .
`; ~'~ "'":' . `' -, . ' ' .- , ' .

- ~ 2~

1 before stated, it is to be understood that it is merely `7 illusteative of the presently preferred embodiments o the :3 invention and that no limitations aee intended to the details ~ o construction or design herein shown other than as defined in 6 the appended claims.

ll 16 .

, '".
:

Claims (27)

1. A laser source which comprises:
a laser diode;
an oscillator optically connected to said laser diode for establishing a beam comprising a plurality of pulses of monochromatic light;
a dispersion line optically connected to said oscillator to receive said pulses;
a regenerative amplifier optically connected to said dispersion line; and a pulse compressor optically connected to said regenerative amplifier for establishing a pulse length for said beam.
2. A laser source as cited in claim 1 comprising a plurality of laser diodes, each of said laser diodes being optically connected to said oscillator.
3. A laser source as cited in claim 2 wherein said oscillator comprises an acousto-optic mode locker for generating said pulses.
4. A laser source as cited in claim 3 wherein said, regenerative amplifier comprises means for establishing a repetition rate for said pulses.
5. A laser source as cited in claim 4 wherein said pulse compressor comprises means for varying the duration of each of said pulses received by said means.
6. A laser source as cited in claim 5 wherein said means for establishing a repetition rate for said pulses is an electro-optical crystal.
7. A laser source as cited in claim 6 wherein said means for varying pulse duration comprises a grating and a corner cube moveable relative to said grating to establish the pulse duration.
8. A laser source as cited in claim 7 further comprising a frequency doubler optically connected to said pulse compressor to provide a plurality of pulsed laser beams.
9. A laser source as cited in claim 8 wherein said dispersion line is a monomode optical fiber.
10. A multiwavelength laser source which comprises:
means for originating a beam of light-frequency radiation pulses having a plurality of discrete wavelengths;
means for spreading the wavelengths of said light-frequency radiation pulses, said spreading means optically connected to said originating means;
means for setting the repetition rate of said light-frequency radiation pulses, said setting means being optically connected to said spreading means; and means for establishing the duration of each of said pulses, said duration establishing means being optically connected to said setting means.
11. A laser source as cited in claim 10 wherein said originating means is an oscillator.
12. A laser source as cited in claim 11 wherein said spreading means is a dispersion line.
13. A laser source as cited in claim 12 wherein said setting means is a regenerative amplifier.
14. A laser source as cited in claim 13 wherein said establishing means is a pulse compressor.
15. A laser source as cited in claim 14 wherein said oscillator comprises a YSGG:Cr:Nd:Er crystal for simultaneously lasing light with an infrared wavelength component and a visible wavelength component.
16. A laser source as cited in claim 15 wherein said originating means comprises an array of laser diodes and an acousto-optic mode locker.
17. A laser source as cited in claim 16 wherein said setting means comprises an electro-optical crystal.
18. A laser source as cited in claim 17 further comprising a frequency doubler for halving the wavelengths of said light-frequency radiation pulses.
19. A laser source as cited in claim 18 further comprising means to select said visible wavelength component for internal ablation and select said infrared wavelength component for external ablation.
20. A laser source which comprises:
means for originating a beam of light-frequency radiation pulses;
means for spreading the wavelengths of said light-frequency radiation pulses, said spreading means optically connected to said originating means;
means for setting the repetition rate of said light-frequency radiation pulses, said setting means being optically connected to said spreading means; and means for establishing the duration of each of said pulses, said duration establishing means being optically connected to said setting means.
21. A laser source as cited in claim 20 wherein said originating means is an oscillator.
22. A laser source as cited in claim 21 wherein said spreading means is a dispersion line.
23. A laser source as cited in claim 22 wherein said setting means is a regenerative amplifier.
24. A laser source as cited in claim 23 wherein said establishing means is a pulse compressor.
25. A method for creating a laser beam which comprises the steps of:
(A) Directing monochromatic light through a mode locker to create a beam of light-frequency radiation pulses having a plurality of discrete wavelengths;
(B) Spreading the wavelengths of the light within each of said pulses;
(C) Setting the repetition rate of aforesaid light-frequency radiation pulses; and (D) Establishing the duration of each of said light-frequency radiation pulses.
26. A method for creating a laser beam as cited in claim 25 wherein said repetition rate is greater than ten thousand pulses per second.
27. A method for creating a laser beam as cited in claim wherein the duration of said light-frequency radiation pulses is less than forty picoseconds.
CA000578516A 1988-01-27 1988-09-27 Multiwavelength laser source Expired - Fee Related CA1291254C (en)

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US07/148,866 US4764930A (en) 1988-01-27 1988-01-27 Multiwavelength laser source

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US4764930A (en) 1988-08-16

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